“…Oncology patients diagnosed with breast, gynecological, gastrointestinal, and lung cancer often experience ≥ 10 symptoms associated with the disease or treatment. 1 , 2 Even though an individual symptom may account for a significant amount of distress, the occurrence of multiple symptoms often results in a high symptom burden, significant impairment in functioning, and poorer quality of life. 1 There is an urgent need to identify the underlying mechanisms for symptoms in order to design effective symptom management.…”