2010
DOI: 10.1007/s10549-010-0973-1
|View full text |Cite
|
Sign up to set email alerts
|

Sentinel lymph node identification with radiopharmaceuticals in patients with breast cancer: a comparison of 99mTc-tin colloid and 99mTc-phytate efficiency

Abstract: Sentinel lymph node biopsy with lymphoscintigraphy has become the standard method for the detection of axillary lymph node metastasis in breast cancer patients. However, there is no standardized radiopharmaceutical. For the detection of axillary lymph node metastasis by lymphoscintigraphy and sentinel node biopsy in patients with breast cancer, we compared the results between subareolar injection of (99m)Tc-tin colloid and injection of (99m)Tc-phytate. This study included 516 breast cancer patients who underwe… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

2
14
0
7

Year Published

2012
2012
2020
2020

Publication Types

Select...
5
1

Relationship

0
6

Authors

Journals

citations
Cited by 17 publications
(23 citation statements)
references
References 14 publications
2
14
0
7
Order By: Relevance
“…The uptake mechanism of 99m Tc phytate is believed to rely upon in vivo colloid formation via chelation with the divalent ion Ca 2+ in the blood in a manner that is similar to the free ligand; thus, it behaves as an RE agent [24]. The 99m Tc phytate has been used for visualization of the RE system, mainly the liver [25], and for sentinel lymph node mapping in melanoma, breast cancer [14], vulvar cancer [26] and lung cancer [27]. The accumulation of the radiopharmaceutical by select organ systems depends on the chemical characteristics and the pathophysiological status of the subject under investigation.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The uptake mechanism of 99m Tc phytate is believed to rely upon in vivo colloid formation via chelation with the divalent ion Ca 2+ in the blood in a manner that is similar to the free ligand; thus, it behaves as an RE agent [24]. The 99m Tc phytate has been used for visualization of the RE system, mainly the liver [25], and for sentinel lymph node mapping in melanoma, breast cancer [14], vulvar cancer [26] and lung cancer [27]. The accumulation of the radiopharmaceutical by select organ systems depends on the chemical characteristics and the pathophysiological status of the subject under investigation.…”
Section: Discussionmentioning
confidence: 99%
“…However, 99m Tc-labeled colloid agent is difficult to obtain in our country, which necessitates the identification of valid alternatives. 99m Tc phytate is occasionally used as a substitute for lymphoscintigraphy [14]. To the best of our knowledge, no study has been conducted using 99m Tc HMPAO LS/ 99m Tc phytate BMS to diagnose infected knee joint replacements.…”
Section: Introductionmentioning
confidence: 99%
“…(INCA, 2009), (SAMPHAO et al, 2008) A média de idade dos nossos pacientes foi de aproximadamente 54 anos, o que é similar ao descrito na literatura, a qual evidencia a ocorrência de CA de mama em populações mais maduras, com média de idade variando entre 47 e 56 anos. (SEOK et al, 2010), (NALASHIMAN et al, 2010), (NOGUCHI et al, 2010), (SEOK et al, 2009) Segundo o INCA (2009) a idade continua sendo um dos principais fatores de risco do CA de mama. As taxas de incidência aumentam rapidamente até os 50 anos e posteriormente, este aumento ocorre lentamente.…”
Section: Características Clínicas E Demográficasunclassified
“…Estes valores estão de acordo com a literatura, que evidencia em ordem decrescente de freqüência o CDI, seguido pelo CDIS, CLI e, então, os demais tipos histológicos. (SEOK et al, 2010), (NALASHIMAN et al, 2010), (NOGUCHI et al, 2010), (SEOK et al, 2009), (ABDOLLAHI et al, 2009) Quanto ao grau histológico do tumor presente nos pacientes submetidos ao estudo, de acordo com a classificação de Scarff-Bloom-Richardson modificado por Elston-Ellis, a maioria apresentou grau II (48,6%), seguido do grau I e grau III com 25,7% cada. Na literatura o grau histológico é variável e depende do tipo de estudo abordado.…”
Section: Características Clínicas E Demográficasunclassified
See 1 more Smart Citation