Separation and concentration of succinic acid from post-fermentation broth by bipolar membrane electrodialysis (EDBM)

Szczygiełda, Mateusz; Antczak, Jerzy; Prochaska, Krystyna

doi:10.1016/j.seppur.2017.03.018

Cited by 67 publications

(16 citation statements)

References 34 publications

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“…The regenerated acids from BMED usually have a low concentration and purity and cannot be appropriately reused. Regarding the conversion of organic or amino acid by BMED, many experimental‐scale studies exist in the literature for citric acid, 18 salicylic acid, 19 formic acid, 20 niacin, 21 alpha‐ketoglutaric acid, 22 succinic acid, 23 and aldonic acid, 24 and some studies have examined batch‐scale or even pilot‐scale production of gluconic acid, 25 malic acid, 26 and methionine 27 . However, previous studies have mainly focused on the conversion of single or both organic/amino acids, but detailed studies of more than two organic/amino acids with different numbers of methylated groups has never been conducted.…”

Section: Introductionmentioning

confidence: 99%

Bipolar membrane electrodialysis for cleaner production of N‐methylated glycine derivative amino acids

Wang

Yan

et al. 2020

AIChE Journal

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In this study, cleaner production of N-methylglycine (NMG), N,N-dimethylglycine (DMG), and N,N,N-trimethylglycine (TMG) with similar structures but different methylate groups was performed using bipolar membrane electrodialysis (BMED). The effects of the feed mass concentration and current density on the separation performance were intensively analysed in terms of the molecular size, molecular structure, ion concentration, and interaction between amino acids and membranes. The results indicated that the optimal recovery performance was achieved at a current density of 200 A/m 2 and feed mass concentration of 6%. Under the optimal conditions, the energy consumption and current efficiencies were 2.3 kWh/kg and 78% for NMG, 2.49 kWh/kg and 69.5% for DMG, and 3.52 kWh/kg and 39.6% for TMG, respectively. It was speculated a competition for water splitting occurs between the bipolar membranes and anion exchange membranes when BMED is used for the separation and purification of large-sized bioproducts.

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Section: Introductionmentioning

confidence: 99%

Bipolar membrane electrodialysis for cleaner production of N‐methylated glycine derivative amino acids

Wang

Yan

et al. 2020

AIChE Journal

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“…The key components determining the efficiency of the electrodialytic recovery process are the applied membranes. In laboratory research dedicated to analyze organic acid recovery from a production method, the possibility is not necessarily given to choose from a wide range (Novalic et al 1996;Madzingaidzo et al 2002;Hbǒvá et al 2004;Zelić and Vasić-Rački 2005;Timbuntam et al 2008;Lameloise and Lewandowski 2012;Sun et al 2017), and it is also worth mentioning the ion-exchange membranes from the ACS Ltd. (Zelić and Vasić-Rački 2005;Prochaska and Woźniak-Budych 2014;Woźniak and Prochaska 2014;Szczygiełda et al 2017).…”

Section: Bipolar Membrane Electrodialysismentioning

confidence: 99%

Low-waste fermentation-derived organic acid production by bipolar membrane electrodialysis—an overview

2021

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Organic acids, e.g, citric acid, fumaric acid, lactic acid, malic acid, pyruvic acid and succinic acid, have important role in the food industry and are potential raw materials for the sustainable chemical industry. Their fermentative production based on renewable raw materials requires innovatively designed downstream processing to maintain low environmental impact and resource efficiency throughout the production process. The application of bipolar membranes offers clean and effective way to generate hydrogen ions required for free acid production from its salt. The water dissociation reaction inside the bipolar membrane triggered by electric field plays key role in providing hydrogen ion for the replacement of the cations in organic acid salts. Combined with monopolar ion-exchange membranes in a bipolar membrane electrodialysis process, material flow can be separated beside the product stream into additional reusable streams, thus minimizing the waste generation. This paper focuses on bipolar membrane electrodialysis applied for organic acid recovery from fermentation broth.

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“…There are some data on removal of inhibitors from lignocellulosic hydrolyzates by electrodialysis [45], recovery of succinic acid, which is an important biorefinery platform chemical [46][47][48].…”

Section: Inhibitor Removalmentioning

confidence: 99%

Electro-membrane separations in biotechnology

Lazarova

Beschkov

Велизаров

2020

Physical Sciences Reviews

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Membrane processes are of crucial importance for downstream processing in biotechnology. This is due to their selectivity and the mild operating conditions, enabling to extract target products without damages caused by overheating and chemical agents. Besides the most spread membrane processes like ultrafiltration and reverse osmosis, electrodialysis is very important for removal and extraction of electrically charged products, i. e. anions of organic acids, some antibiotics, etc. The electrodialysis process can be organized in batch or continuous mode. On the other hand, in the electro-crossflow filtration, the transport of target solutes across the membrane is guided by two main driving forces, the transmembrane pressure and the electric potential. This combination enables various possibilities for more selective and efficient downstream processing in biotechnology. This chapter provides a brief overview of recent achievements of electrodialysis in selected bioproducts separations and recovery. A special focus, including original experimental data, is then given to electro-filtration, which is a powerful tool creating new opportunities for performing separations on the basis of both electric charge and particle size differences.

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Separation and concentration of succinic acid from post-fermentation broth by bipolar membrane electrodialysis (EDBM)

Cited by 67 publications

References 34 publications

Bipolar membrane electrodialysis for cleaner production of N‐methylated glycine derivative amino acids

Bipolar membrane electrodialysis for cleaner production of N‐methylated glycine derivative amino acids

Low-waste fermentation-derived organic acid production by bipolar membrane electrodialysis—an overview

Electro-membrane separations in biotechnology

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