Separation efficiency versus resolution: Chiral separation of gamma lactones by capillary GC on derivatized cyclodextrin

Abstract

In conclusion, we have decreased the analysis time required for the complete separation and quantitation of the volatile compounds normally analyzed by EPA Method 502.2. In most cases the lower limit of detection was improved over the published and standardized methodology. This automated procedure is used routinely in our laboratory and provides rapid quantitative and automated determination of these compounds.

Diluted versus undiluted cyclodextrin derivates in capillary gas chromatography and the effect of linear carrier gas velocity, column temperature, and length on enantiomer separation

“…Earlier investigations [7,8] showed a strong temperature dependence of the separation factors, suggesting that the lowest possible operating temperature should be used. The normally long retention times could be reduced by decreased column length or increased linear carrier gas velocities.…”