Separation of a high-value pharmaceutical compound from waste ethanol by nanofiltration

Evaluation of reverse osmosis and nanofiltration membranes performance in the permeation of organic solvents

“…The main applications include solvent recovery from micelles of vegetable oil/organic solvents; deacidification and clarification of vegetable oils [1][2][3] and separation of natural compounds from essential oils [4,5]. However, there are still few reports on the application of membranes in the separation of non-aqueous streams in industrial level.…”

“…Extension of conventional steric and electrostatic separation mechanisms, typical of aqueous environments, to non-aqueous systems is complex, due to the significant differences in the structures and properties of the solvents [1,2]. Several authors have observed that membranes performance is less predictable in the presence of organic solvents than in aqueous solutions [1,2,[4][5][6], and the MMCO is an insufficient descriptor for the separation capability of the membrane in organic solvents. Compared to the aqueous membrane process, non-aqueous processes are categorised by the increase in the number of solute-solvent-membrane interactions, which play a determining role in the understanding of both solvent flux and solute rejection [6].…”

Nanofiltration – Theory and Application

“…Specifi c applications include polymeric NF diafi ltration for demineralization and purifi cation of quaternary ammonium salt solutions [175], demineralization of amino acid solutions [16], and recovery of pharmaceutically active products [55,[176][177][178][179][180]. Similar to the dairy and sweetener industry, NF can be used for fractionation, purifi cation, demineralization and concentration, and is often integrated with other membrane processes such as MF and UF.…”

Evaluación ecotoxicológica de aguas residuales industriales del Centro de Bioactivos Químicos (Santa Clara, Cuba) en Artemia sp.

“…Su principal renglón productivo es el ingrediente farmacéutico activo furvina (1-(5-bromo-fur-2-il)-2-bromo-2-nitroetano), el cual, durante su proceso de obtención, genera varios flujos de residuos, que son procesados en una planta de tratamiento de aguas residuales, con el fin de disminuir los niveles de contaminantes. Los tratamientos se basan en procesos químico-físicos, como la dilución y neutralización, para disminuir el carácter tóxico de los flujos de residuos concentrados (Martínez, Van der Bruggen, Negrin, & Alconero, 2012).…”