Separation of three water‐soluble vitamins by poly(dimethylsiloxane) microchannel electrophoresis with electrochemical detection

Li, Xiangyun; Zhang, Qianli; Lian, Huibo; Xu, Jing‐Juan; Chen, Hong‐Yuan

doi:10.1002/jssc.200700155

Cited by 7 publications

(5 citation statements)

References 31 publications

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“…These substances may participate in enzymatic processes as co‐enzymes or their precursors, act as antioxidants, and affect genetic regulation processes. Therefore, absence of vitamins will cause serious physiological problems 1, 2. Among all kinds of vitamins, the B group of vitamins is the most important constituent, endowed with a great variety of chemical structures.…”

Section: Introductionmentioning

confidence: 99%

“…There are a great variety of analytical methods based on spectrophotometry 3, fluorimetry 4, electrochemistry 5, 6, capillary electrophoresis and chip electrophoresis 2, 7, HPLC 8, 9 and mass spectrometry 10 monitoring the overall quantification of the given vitamin B samples. However, some of these methods only offer the possibility of individual or two quantifications of the given analytes.…”

Section: Introductionmentioning

confidence: 99%

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All‐Metal Clusters that Mimic the Chemistry of Halogens

Zhao

Wang

et al. 2013

ChemPhysChem

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Owing to their s(2)p(5) electronic configuration, halogen atoms are highly electronegative and constitute the anionic components of salts. Whereas clusters that contain no halogen atoms, such as AlH(4), mimic the chemistry of halogens and readily form salts (e.g., Na(+)(AlH(4))(-)), clusters that are solely composed of metal atoms and yet behave in the same manner as a halogen are rare. Because coinage-metal atoms (Cu, Ag, and Au) only have one valence electron in their outermost electronic shell, as in H, we examined the possibility that, on interacting with Al, in particular as AlX(4) (X=Cu, Ag, Au), these metal atoms may exhibit halogen-like properties. By using density functional theory, we show that AlAu(4) not only mimics the chemistry of halogens, but also, with a vertical detachment energy (VDE) of 3.98 eV in its anionic form, is a superhalogen. Similarly, analogous to XHX superhalogens (X=F, Cl, Br), XAuX species with VDEs of 4.65, 4.50, and 4.34 eV in their anionic form, respectively, also form superhalogens. In addition, Au can also form hyperhalogens, a recently discovered species that show electron affinities (EAs) that are even higher than those of their corresponding superhalogen building blocks. For example, the VDEs of M(AlAu(4))(2)(-) (M=Na and K) and anionic (FAuF)Au(FAuF) range from 4.06 to 5.70 eV. Au-based superhalogen anions, such as AlAu(4)(-) and AuF(2)(-), have the additional advantage that they exhibit wider optical absorption ranges than their H-based analogues, AlH(4)(-) and HF(2)(-). Because of the catalytic properties and the biocompatibility of Au, Au-based superhalogens may be multifunctional. However, similar studies that were carried out for Cu and Ag atoms have shown that, unlike AlAu(4), AlX(4) (X=Cu, Ag) clusters are not superhalogens, a property that can be attributed to the large EA of the Au atom.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

All‐Metal Clusters that Mimic the Chemistry of Halogens

Zhao

Wang

et al. 2013

ChemPhysChem

View full text Add to dashboard Cite

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“…There are a great variety of analytical methods based on spectrophotometry [3], fluorimetry [4], electrochemistry [5,6], capillary electrophoresis and chip electrophoresis [2,7], HPLC [8,9] and mass spectrometry [10] monitoring the overall quantification of the given vitamin B samples. However, some of these methods only offer the possibility of individual or two quantifications of the given analytes.…”

Section: Introductionmentioning

confidence: 99%

“…These substances may participate in enzymatic processes as coenzymes or their precursors, act as antioxidants, and affect genetic regulation processes. Therefore, absence of vitamins will cause serious physiological problems [1,2]. Among all kinds of vitamins, the B group of vitamins is the most important constituent, endowed with a great variety of chemical structures.…”

Section: Introductionmentioning

confidence: 99%

Assay of vitamin B in urine by capillary electrochromatography with methacrylate‐based monolithic column

Wei

Qiao

et al. 2010

Electrophoresis

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A novel and simple method for the separation of major vitamin B analytes, such as thiamine, riboflavin, nicotinamide, vitamin B4, pyridoxine, has been developed by CEC using the monolithic column. It has been found that the baseline separation of the five analytes could be achieved with 5.0 mM phosphate buffer at pH 4.0. Compared with the open-tubular capillary and the bared capillary columns, the poly(butylmethacrylate-co-ethylene glycol dimethacrylate) monolithic capillary could exhibit the best resolution in the analysis. Then the method was validated and the linear calibration ranges were obtained with correlation coefficients more than 0.997. The precision and the recovery were also investigated and showed a good result. Furthermore, the proposed method was successfully applied to assay the concentration of vitamin B analytes and the metabolic situation in human urine samples.

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“…[1][2][3][4][5][6] Successful applications of PDMS microchip CE include, but not limited to, environmental, genetic, clinical, and pharmaceutical analyses. 2,[7][8][9][10][11][12][13] However, many PDMS microfluidic platforms suffer from sample adsorption onto the PDMS surface and penetration into the PDMS matrix.…”

Section: Introductionmentioning

confidence: 99%

Modification of Electroosmotic Flow for a Polydimethylsiloxane Electrophoresis Microchip via Polyelectrolyte Coating

et al. 2012

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Polydimethylsiloxane has been dominantly employed as the substrate material for microchip capillary electrophoresis. The poor surface chemistry, however, generates inconsistent electroosmotic flow under the electrophoretic condition, limiting its broader applications. In this work, different polyelectrolytes, including polydiallyldimethylammonium chloride, polyvinyl sulfate, and dextran sulfate, were successfully deposited onto polydimethylsiloxane microchannel surfaces. The polyelectrolyte coated polydimethylsiloxane microchannel showed improved consistency and reproducibility in electroosmotic flow under an electric field over the uncoated native microchannel.

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Separation of three water‐soluble vitamins by poly(dimethylsiloxane) microchannel electrophoresis with electrochemical detection

Cited by 7 publications

References 31 publications

All‐Metal Clusters that Mimic the Chemistry of Halogens

All‐Metal Clusters that Mimic the Chemistry of Halogens

Assay of vitamin B in urine by capillary electrochromatography with methacrylate‐based monolithic column

Modification of Electroosmotic Flow for a Polydimethylsiloxane Electrophoresis Microchip via Polyelectrolyte Coating

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