Separation, structure characterization, conformation and immunomodulating effect of a hyperbranched heteroglycan from Radix Astragali

Decoding glycome of Astragalus membranaceus based on pressurized liquid extraction, microwave-assisted hydrolysis and chromatographic analysis

“…These results were consistent with previous studies of the purified polysaccharides from A. membranaceus that were mainly glucans or heteropolysaccharides composed of glucose, galacturonic acid, arabinose, rhamnose and galactose [11][12][13][14][15][16][17][18][19][20]. As quantification of polymeric carbohydrates after hydrolysis in A. membranaceus has not been studied before, it can offer considerable information in decoding the glycome of A. membranaceus and can be very beneficial for its quality control [5].…”

“…Polysaccharides are the main bioactive ingredients in A. membranaceus and have been proven to have multiple pharmacological activities, especially tonic effects [7][8][9][10]. Several studies have been carried out on the analysis of polysaccharides from A. membranaceus [11][12][13][14][15][16][17][18][19][20]. However, most of those works only focused on the purified polysaccharides.…”

Structure Characterization of Honey-Processed Astragalus Polysaccharides and Its Anti-Inflammatory Activity In Vitro

“…The honey-processed Astragalus and radix Astragalus were crushed into powders, respectively. The polysaccharide was isolated from Astragalus by hot-water extraction and ethanol precipitation [ 19 ]. The dried powder was first immersed in 70% ethanol at 80 °C for 1 h to remove the pigments and small organic compounds, then extracted with distilled water.…”

Structural Characterization, Antioxidant Activity, and Biomedical Application of Astragalus Polysaccharide Degradation Products

“…The two distinct absorbance peaks, at about 1616.7 and 1417.9 cm −1 , suggested the presence of uronic acids. The absorption peaks at 1113.7 and 1027.7 cm −1 indicate that the polysaccharide contains α-glucose residues [30].…”