Sepse na unidade de terapia intensiva: etiologias, fatores prognósticos e mortalidade

Zanon, Fernando; Caovilla, Jairo José; Michel, Regina Schwerz; Cabeda, Estêvan Vieira; Ceretta, Diego Francisco; Luckemeyer, Graziela Denardin; Beltrame, Cássia; Posenatto, Naiana

doi:10.1590/s0103-507x2008000200003

Cited by 56 publications

(55 citation statements)

References 23 publications

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“…No que se refere aos diagnósticos de internação, resultado semelhante a este estudo foi encontrado em outra investigação 10 Interessante destacar que, na instituição investigada na presente pesquisa, já existe uma unidade de cardiologia intensiva, para onde são encaminhados pacientes com dano cardiovascular. Dessa forma, os dados encontrados são relativos à internação em UTI geral, excluindo-se as patologias cardíacas.…”

Section: Discussionunclassified

“…Em relação às infecções, em outros estudos 6,10 observaram-se taxas um pouco maiores de infecções com 53,4% e 53,8% respectivamente. Diferentemente do presente estudo, outra investigação realizada sobre o tema 6 , aponta que o sitio mais prevalente foi o urinário, com 43%; em segundo lugar apareceu a pneumonia associada à ventilação mecânica com 30% e a infecção da corrente sanguínea incidiu em 14% da população estudada.…”

Section: Discussionunclassified

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Perfil dos pacientes internados na unidade de terapia intensiva adulto de um hospital universitário

Favarin

Camponogara²

2012

Rev Enferm UFSM

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Section: Discussionunclassified

Perfil dos pacientes internados na unidade de terapia intensiva adulto de um hospital universitário

Favarin

Camponogara²

2012

Rev Enferm UFSM

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“…Median APACHE II score for all patients was 21 (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28). Non-survivor patients had a median APACHE II score that was signifi cantly higher (27; …”

Section: Resultsmentioning

confidence: 99%

The epidemiology of sepsis in a Brazilian teaching hospital

Kauss¹,

Grion²,

Cardoso³

et al. 2010

Braz J Infect Dis

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We declare no confl ict of interest. ABSTRACT Objectives:The objective of this study was to estimate disease incidence and mortality rate of sepsis in a tertiary public hospital. Methods: Patients admitted to the Intensive Care Unit (ICU) in 2004 and 2005 were monitored for sepsis using an observational longitudinal study design. Patients were monitored daily for diagnostic criteria of sepsis, according to ACCP/SCCM Consensus Conference criteria, until either death or hospital discharge. Results: During the study, we analyzed 1,179 patients. Systemic Infl ammatory Response Syndrome (SIRS) was present in 1,048 (88.9%) patients on admission, and was associated with infection in 554 (47.0%) patients. Of these, sepsis was diagnosed in 30 (2.5%) patients, while severe sepsis was diagnosed in 269 (22.8%) patients, and septic shock was diagnosed in 255 (21.6%) patients. APACHE II and SOFA scores were higher in septic patients (p < 0.001), and the ensuing mortality rates were 32.8% (IC 95%: 21.6-45.7%) for patients with sepsis, 49.9% (IC 95%: 44.5-55.2%) for severe sepsis, and 72.7% (IC 95%: 68.1-76.9%) for septic shock. Conclusions: The data from our study revealed a high incidence of sepsis among hospitalized patients. Moreover, sepsis patients had a high rate of mortality.

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“…Studies conducted in different regions confirm this distribution. 18,21,27,28 The literature suggests that there is a strong relationship between the time between organic dysfunction and the diagnosis of sepsis, as well as the time between antibiotic administration and mortality. 29 After the intervention, it was observed that providers in the emergency department made an earlier diagnosis of sepsis, with only 30 minutes from the time of dysfunction until the diagnosis; in the ICU, the time of administration of antibiotics reached approximately 12 minutes.…”

Section: Discussionmentioning

confidence: 99%

The Use of an Educational Tool to Improve Adjustment to the Sepsis Protocol and the Clinical Impact

Veríssimo¹,

Sobrinho²,

Andrade³

et al. 2017

NCOAJ

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Introduction: Sepsis is a major global health problem and is responsible for the deaths of thousands of people each year. It is the second leading cause of death in intensive care units, after coronary heart disease. Due to the high mortality rate, sepsis needs to be addressed through evidence-based practice, institutionalized protocols, well-developed clinical strategies, and continuing education. This study analyzed the clinical impact of adherence to an education tool for sepsis control measures at the Adventist Hospital of Belém in Brazil. Methodology:A prospective, quasi-experimental study was carried out from March to December 2015. The study included 152 patients diagnosed as having selection criteria with suspected sepsis. The patients diagnosed in the emergency department of the hospital were divided into a control group (n=30) and a case group (n=122) based on the period in which an educational tool was applied, for adherence to the hospital sepsis protocol. Results:The best adherence measure, after the tool application, was antimicrobial therapy. There was a reduction in the hospitalization time of the surviving patients from 19.7 days to 7.7 days and the mortality rate decreased from 63.3% to 30.6%. Conclusion:Although adherence to resuscitation packages was low, the education tool increased the insight of professionals in the identification of septic patients, resulting in a diagnosis and early treatment that corresponded with a reduction in hospitalization time and a decrease in mortality. The implementation of the educational tool and feedback letter was performed in August 2015. Patients admitted from March to July 2015, the period prior to the use of the tool, were eligible for participation in the control group, while patients admitted from August to December 2015 were eligible for participation in the case group. All adult patients greater than 18 years of age and diagnosed with sepsis, severe sepsis, and septic shock, admitted from the emergency department or transferred to the ICU within the first 24 hours of the diagnosis, were included in the study. The criteria for defining sepsis were based on the Sepsis Survival campaign (CSS) criteria. Obstetric patients, patients with sepsis referred from other institutions, and patients with organic dysfunctions not considered secondary to a chronic disease were excluded. KeywordsThe compilation of clinical and demographic data was conducted through the patients' clinical histories, using the form designed by the Institute Latin American Sepsis (ILAS) 9 and adapted by hospital quality management in conjunction with the Hospital Infection Control Committee (CCIH). From the time that the patient with suspected sepsis was admitted to the hospital, the CCIH team was activated and the data was collected using the pre-designed form. The evaluation was based on compliance with the updated CSS resuscitation package from 2012. The package also includes requirements that must be met within the first three and six hours, which are comprised of diagnosti...

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Sepse na unidade de terapia intensiva: etiologias, fatores prognósticos e mortalidade

Cited by 56 publications

References 23 publications

Perfil dos pacientes internados na unidade de terapia intensiva adulto de um hospital universitário

Perfil dos pacientes internados na unidade de terapia intensiva adulto de um hospital universitário

The epidemiology of sepsis in a Brazilian teaching hospital

The Use of an Educational Tool to Improve Adjustment to the Sepsis Protocol and the Clinical Impact

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