2024
DOI: 10.14814/phy2.15964
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Sepsis‐associated encephalopathy: Autophagy and miRNAs regulate microglial activation

Nannan Qin,
Yanmei Miao,
Leiyu Xie
et al.

Abstract: Sepsis‐associated encephalopathy (SAE) describes diffuse or multifocal cerebral dysfunction caused by the systemic inflammatory response to sepsis. SAE is a common neurological complication in patients in the middle and late stages of sepsis in the intensive care unit. Microglia, resident macrophages of the central nervous system, phagocytose small numbers of neuronal cells and apoptotic cells, among other cells, to maintain the dynamic balance of the brain's internal environment. The neuroinflammatory respons… Show more

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