Sepsis Secondary to<i>Bacteroides Fragilis</i>Tubo-Ovarian Abscess Requiring Hysterectomy and Bilateral Salpingo-Oophorectomy

Feuerstein, J.; O’Gorman, Julianne; Jakus, Jonathan

doi:10.1136/bcr-2017-222460

Cited by 4 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Firmicutes has high content of peptidoglycan in the cytoderm, which is generally regarded as a beneficial bacteria [ 31 ]. However, Bacteroides can cause infection when the immune function of the body is disturbed or the microbiota is imbalanced [ 32 ]. Our results indicated that L. rhamnosus TR08 pretreatment could increase the abundance of bacteria in the gut of septic mice.…”

Section: Discussionmentioning

confidence: 99%

Lacticaseibacillus rhamnosus TR08 alleviated intestinal injury and modulated microbiota dysbiosis in septic mice

Yin

Sun

et al. 2021

BMC Microbiol

View full text Add to dashboard Cite

Background Probiotics are widely used in intestinal microbiota imbalance caused by sepsis, however, the protective mechanism is still unclear. This study aimed to explore protective effect of Lacticaseibacillus rhamnosus TR08 on intestinal injury in septic mice. Results The levels of serum inflammatory factors were reduced significantly in septic mice treated with L. rhamnosus TR08. The levels of sIgA in terminal ileum were significantly higher in probiotic treatment group than sepsis group. Intestinal pathological damage in septic mice improved and the expression of tight junction proteins increased after probiotic treatment. Sequencing of fecal microbiota showed that the abundance and diversity of probiotic treatment group were significantly better than those of sepsis group, and beneficial bacteria increased while some bacteria decreased in the phylum level. Conclusion L. rhamnosus TR08 could improve the integrity of intestinal barrier, enhance the intestinal mucosal immunity in septic mice, and rebalance the intestinal microecosystem.

show abstract

Section: Discussionmentioning

confidence: 99%

Lacticaseibacillus rhamnosus TR08 alleviated intestinal injury and modulated microbiota dysbiosis in septic mice

Yin

Sun

et al. 2021

BMC Microbiol

View full text Add to dashboard Cite

show abstract

“…Contrary to this, however, among the 56 patients in our dataset, any STI (gonorrhea, chlamydia, and/or trichomonas) was present in only 12 cases (25%). In some instances, severe pelvic infections (including the entities of THPO) have been shown to result from bacteria typically found in the normal vaginal flora [ 14 - 15 ]. This might explain lower than presumed rates of STIs observed in our cohort of THPO patients.…”

Section: Discussionmentioning

confidence: 99%

Epidemiologic and Clinical Characteristics of Tubo-Ovarian Abscess, Hydrosalpinx, Pyosalpinx, and Oophoritis in Emergency Department Patients

Mohseni

Simon

Sheele

2020

Cureus

View full text Add to dashboard Cite

Introduction Pelvic inflammatory disease (PID) is a spectrum of illness ranging from mild illness to more severe forms including tubo-ovarian abscess, hydrosalpinx, pyosalpinx, oophoritis (THPO). The objective of the study was to report rates and clinical characteristics of females presenting to the ED with a diagnosis of THPO in relationship to the presence or absence of sexually transmitted infections (STIs). Methods A database of ED patient encounters occurring from April 18, 2014, to March 7, 2017 was created. Analysis of women diagnosed with THPO and who had testing for gonorrhea, chlamydia, or trichomonas by nucleic acid amplification testing or who had a vaginal wet preparation was performed. Patient demographics, ED diagnoses, laboratory tests, medications administered in the ED, and medications prescribed were examined. Categorical variables were summarized as count and percentages and analyzed using the Chi-square test. Continuous variables were summarized as the mean and standard deviation and analyzed using the t-test. All statistical tests were two-sided with a significance level of 0.05. Results THPO was diagnosed in 0.3% (56/17,905) of patient encounters. There were 50% (28/56) of women with THPO admitted to the hospital. There were 25.0% (12/48) women who received a positive test result for Neisseria gonorrhoeae, Chlamydia trachomatis, and/or Trichomonas vaginalis. Women with THPO were significantly older, more likely to be infected with gonorrhea, and more likely to be diagnosed with sepsis and PID (P<.05 for all). Conclusions THPO is an infrequently encountered entity in the ED. A diagnosis of STI, PID, and sepsis can accompany these presentations. Although an uncommon diagnosis, ED providers must be attentive to patients presenting with pelvic symptoms that could be consistent with THPO to mitigate any complications that may arise and to direct the appropriate treatment.

show abstract

“…Pelvic inflammatory disease itself is rarely associated with sepsis. However, tuboovarian abscess that arise from pelvic inflammatory disease can progress into sepsis, especially when ruptured [7]. Ruptured tubo-ovarian abscesses, pyometra or pyomyoma that led to sepsis or septic shock have been reported in some case reports or case series [8,9].…”

Section: Discussionmentioning

confidence: 99%

Septic shock caused by abscess formation inside cystic adenomyosis after responsive treatment of pelvic inflammatory disease

Song,

Lee,

Yang

et al. 2020

Clin. Exp. Obstet. Gynecol.

View full text Add to dashboard Cite

Objective: To report on septic shock in a patient with an abscess inside cystic adenomyosis after responsive treatment of pelvic inflammatory disease. Case report: A 51-year-old woman with known cystic adenomyosis was admitted to the hospital due to fever and low abdominal pain. In suspicion of pelvic inflammatory disease, intravenous antibiotics were administered. As her symptoms and sings of inflammation improved, she was discharged from the hospital after five days. However, after completing 14 days of oral antibiotics, her symptoms aggravated with decreased blood pressure. Magnetic resonance imaging indicated abscess formation inside cystic adenomyosis, and total hysterectomy was performed. Postoperatively, she fell into shock condition. Intravenous antibiotics were administered for 11 days and she was discharged from the hospital with no adverse event. Conclusion: Physicians should be aware of the possibility of septic shock caused by abscess formation inside known cystic adenomyosis.

show abstract

Sepsis Secondary toBacteroides FragilisTubo-Ovarian Abscess Requiring Hysterectomy and Bilateral Salpingo-Oophorectomy

Cited by 4 publications

References 11 publications

Lacticaseibacillus rhamnosus TR08 alleviated intestinal injury and modulated microbiota dysbiosis in septic mice

Lacticaseibacillus rhamnosus TR08 alleviated intestinal injury and modulated microbiota dysbiosis in septic mice

Epidemiologic and Clinical Characteristics of Tubo-Ovarian Abscess, Hydrosalpinx, Pyosalpinx, and Oophoritis in Emergency Department Patients

Septic shock caused by abscess formation inside cystic adenomyosis after responsive treatment of pelvic inflammatory disease

Contact Info

Product

Resources

About