Septic Shock Complicating Acute Rotavirus-Associated Diarrhea

Intestinal necrosis due to norovirus enteritis

“…There are several case reports of bacterial sepsis secondary to viral gastroenteritis [9,10]. Rotavirus is known to cause intestinal epithelium dysfunction and rotavirusinfected enterocytes are vulnerable to bacterial invasion [11].…”

Ancillary testing in children with rotavirus gastroenteritis

“…Cultures obtained other than peripheral blood cultures were only positive in 1 patient; this patient also had cellulitis and Escherichia coli was isolated from both blood and wound cultures. 3 One of the reported children with bacteremia died, 2 cases of SBI following RGE were complicated by disseminated intravascular coagulopathy, and 1 case by acute renal failure. Enterobacter cloacae (n ¼ 4) and Klebsiella pneumoniae (n ¼ 3) were the most commonly isolated organisms from peripheral blood culture.…”

“…1 Costly microbiological assays are frequently performed in these patients to exclude concurrent serious bacterial infection (SBI), though the actual incidence of SBI is quite low. [2][3][4][5][6][7][8] Our objectives were to describe the incidence of SBI in children evaluated at a community hospital and subsequently diagnosed with laboratoryconfirmed RGE and to determine whether ancillary testing was associated with prolonged length of stay (LOS) in hospitalized patients.…”

Complications with rotavirus: A single center experiences

“…So, exact incidence of septicemia during the disease is not known. Carneiro et al 17 reported a child who had RG complicated with septic shock due to ESBL positive E. coli. Kashiwagi et al 19 also described Klebsiella sepsis in the course of RG in an infant.…”

“…There are only few case reports in the literature currently regarding septicemia after RG 12,[16][17][18][19] . So, exact incidence of septicemia during the disease is not known.…”