“…Treatment consists in calculus removal along with topical irrigation with antibacterial solutions.1,6 Both conditions may progress to osteomyelitis with pathologic fractures and/or systemic infections,1,2,6,7 leading to spontaneous decease2,7 or to euthanasia. 3,4,8 The progressive reduction of antibiotic efficacy and the search for novel therapeutical approaches have raised interest in regenerative medicine compounds such as platelet-rich blood derivates. Platelet-rich plasma (PRP) is a biologically active product composed of platelets obtained by centrifugation of patient's whole blood and resuspended in plasma characterized by elevated concentrations of growth factors and chemotactic molecules.9-15 PRP has been mostly applied to orthopedical, dermatological, and ophthalmological conditions in horses and dogs and,16-19 have recently gained interest in exotic animal practice.20-22 Our aim was to evaluate the efficacy of thrombocyte-leukocyte rich plasma (TLRP), a PRP compound, in chronic oral cavity disorders in reptiles.…”