“…Clinical case descriptions of disseminated infections due to low-pathogenicity Yersinia in iron-overloaded patients are numerous in the literature. This ironoverload status responsible for disseminating Yersinia infections had different origins: oral overdose of iron (Robins-Browne et al, 1979a;Soriano et al, 1981;Melby et al, 1982;Mofenson et al, 1987); iron therapy (Leighton and MacSween, 1987;Fakir et al, 1995); hemodialysis (Boelaert et al, 1987) and long-term transfusion therapy (Schuchmann et al, 1997); and underlying diseases that increase directly or indirectly (through blood transfusions) the iron burden of the patients: 1) hypersideremia without any known etiology (Sibilia et al, 1991), 2) primary hemochromatosis (Jacquenod et al, 1984;M'Rad et al, 1988;Shibuya et al, 1988;Merrien et al, 1991;Vadillo et al, 1994;Collazo et al, 1995;Piroth et al, 1997;Höpfner et al, 2001), 3) thalassemia (Blum et al, 1970;Hewstone and Davidson, 1972;Seigneurin et al, 1972;Rabson et al, 1975;Bouza et al, 1980;Hambourg et al, 1980;Soriano et al, 1981;Adamkiewicz et al, 1998), 4) autoimmune hemolytic anemia (Guez et al, 1987), and 5) liver diseases (Marlon et al, 1971;Seigneurin et al, 1972;Rabson et al, 1975;Imhoof and Auckenthaler, 1980;Soriano et al, 1981;Jacquenod et al, 1984;Merrien et al, 1991).…”