2022
DOI: 10.1021/acs.jafc.2c02385
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Sequence-Selected C13-Dipeptide Self-Assembled Hydrogels for Encapsulation of Lemon Essential Oil with Antibacterial Activity

Abstract: Supramolecular self-assembling peptide hydrogels are attracting attention. The switching of even one amino acid may lead to differences in structure and functions of peptide hydrogels. Herein, we investigate the effect of substitution of a single amino acid residue on the gelation properties of C 13 -dipeptide hydrogels. We show that four C 13 -R 1 Y (C 13 -VY, C 13 -FY, C 13 -WY, and C 13 -YY) can form hydrogels with drastically tunable rigidity (the G′ values were 5. 74, 0.16, 27.74, and 67.90 KPa, respectiv… Show more

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Cited by 10 publications
(3 citation statements)
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“…Overall, these AFM results confirm the self‐assembly of RADA16‐hempseed peptides, facilitating the slow and sustained release of hempseed hydrolysis products. Four C 13 ‐R1Y (C 13 ‐VY, C 13 ‐FY, C 13 ‐WY, and C 13 ‐YY) were used for the encapsulation of lemon essential oil (LEO) (Hu et al., 2022). Figure 9c shows the cumulative release of peptide hydrogels and free LEO in vitro.…”
Section: Applications Of Peptide Hydrogels In Food Sciencementioning
confidence: 99%
See 1 more Smart Citation
“…Overall, these AFM results confirm the self‐assembly of RADA16‐hempseed peptides, facilitating the slow and sustained release of hempseed hydrolysis products. Four C 13 ‐R1Y (C 13 ‐VY, C 13 ‐FY, C 13 ‐WY, and C 13 ‐YY) were used for the encapsulation of lemon essential oil (LEO) (Hu et al., 2022). Figure 9c shows the cumulative release of peptide hydrogels and free LEO in vitro.…”
Section: Applications Of Peptide Hydrogels In Food Sciencementioning
confidence: 99%
“…(b) Self‐assembly of RADA16‐hempseed hydrolysates (Lammi et al., 2019). (c) Cumulative release of lemon essential oil (LEO) of the peptide‐based hydrogel and free LEO in vitro (Hu et al., 2022).…”
Section: Applications Of Peptide Hydrogels In Food Sciencementioning
confidence: 99%
“…Other approaches have used existing polymers, mainly biopolymers, to build the aqueous phase. In this case, the polymeric network is formed by supramolecular self-assembly (i.e., peptide [18]) and ionic and electrostatic interactions [19][20][21][22] or by using other natural compounds as cross-linkers (i.e., phytic acid [23]).…”
Section: Introductionmentioning
confidence: 99%