Sequential HCoV-HKU1 and SARS-CoV-2 Infections, a Case Report

Abstract

In the SARS-CoV-2 pandemic, the seasonal viral respiratory infections had a minimum prevalence due to public health precautions to reduce the risk of getting Coronavirus Disease 19 (COVID-19). There have been reports of COVID-19 coinfection with influenza, respiratory syncytial virus (RSV), and seasonal coronaviruses during the pandemic. Here, we report a case in which the patient had sequential respiratory infections of human coronavirus HKU1 (HCoV-HKU1) and SARS-CoV-2 in a fully vaccinated, healthy person. It should be noted that other seasonal coronaviruses that could cause symptomatic RTIs might be misdiagnosed clinically with COVID-19. Hence, we highly recommend monitoring and follow-up of symptomatic patients with negative SARS-COV-2 RT-PCR results.

The prevalence of 17 common respiratory viruses in patients with respiratory illness but negative for COVID‐19: A cross‐sectional study

“…Moreover, the HiTeq 17 Viro Respiratory pathogen One‐Step RT‐PCR Kit (GeneovA), made in 2021 in Iran, was used in the present study; other studies have used this kit considering its appropriate sensitivity and specificity to identify various viral respiratory pathogens, including SARS‐CoV‐2, Flu A, Flu B, Flu A/H1N1, HCoV‐NL63, HCoV‐229E, HCoV‐HKU1, HCoV‐229E, HCoV‐OC43, HPiV‐1, ‐2, ‐3, HAdV, HBoV‐1, ‐2, ‐3, HMPV, and HRSV 7,26 …”