Sequential-injection extraction for sample preparation

Analytical methodologies for the determination of sertraline

“…Peterson et al [41] introduces a flow-based extraction method where an aqueous sample and organic solvent are injected sequentially into an extraction coil, then mixed and separated due to the differential flow velocities of the aqueous and organic phases. A 500 L aqueous sample is propelled through a 50 L segment of organic solvent whose flow is impeded due to hydrophobic interactions with the walls of a Teflon extraction coil.…”

Application of sequential-injection analysis as process analyzers

“…Peterson et al [103] described a flow-based extraction method where an aqueous sample and or- ganic solvent were sequentially injected into an extraction coil, mixed, and separated due to the differential flow velocities of the aqueous and organic phases. A 500 lL aqueous sample is propelled through a 50 lL segment of organic solvent whose flow is impeded due to hydrophobic interactions with the walls of a Teflon extraction coil.…”

Application of sequential injection analysis to pharmaceutical analysis

“…carry out determinations over long time periods, for example during the monitoring of industrial processes [19,20]. The versatility shown makes it possible to automate various steps of an analytical procedure, for example: sample dilution [21], automatic calibration [22], gas-liquid diffusion [23], liquid-liquid extraction [24], dialysis [25] and on-line digestion [26]. It is also an adequate technique for multiparametric determinations since different analytical determinations can be easily implemented in the same configuration [27].…”