Sequential injection technique applied to pharmaceutical analysis

Solich, Petr; Polášek, Miroslav; Klimundová, Jana; Růžička, Jaromír

doi:10.1016/s0165-9936(04)00304-8

Cited by 32 publications

(15 citation statements)

References 47 publications

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“…This last attribute of SI makes it ideally suited to clinical and biochemical applications for which sample pretreatment is usually necessary prior to the actual analytical measurement. The general applications of SI in biomedical and pharmaceutical analysis have been reviewed elsewhere [17,18].…”

Section: Sequential Injection Analysismentioning

confidence: 99%

Automated Determination of Pharmaceutically and Biologically Active Thiols by Sequential Injection Analysis: A Review

Tzanavaras

2010

TOCBMJ

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Abstract:The present review article presents and discusses automated sequential injection (SI) based methods for the determination of pharmaceutically and biologically important thiols, namely cysteine, N-acetylcysteine, penicillamine, glutathione and captopril. The review intends to cover a range of ten years of published research on this topic (2000 -2009). The methods are classified according to the detection systems in three categories, namely spectrophotometric, fluorimetric and electroanalytical. The determination principles of the methods are discussed and the main analytical figures of merit are tabulated.

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Section: Sequential Injection Analysismentioning

confidence: 99%

Automated Determination of Pharmaceutically and Biologically Active Thiols by Sequential Injection Analysis: A Review

Tzanavaras

2010

TOCBMJ

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“…Zinc reduction coupled to sequential injection analysis is no doubt a green chemical analytical approach for sustainable development in view of the reduced reagent input and reduced waste generation. The programmable flow derived from sequential injection analysis (SIA) in the lab-on-valve (LOV) format is a fast-growing technology in chemical process disciplines as micro-SIA-LOV minimizes resource consumption and waste generation much more than flow injection analysis (FIA) and also offers a stopflow mode for slow reactions (Solich et al 2003).…”

Section: Introductionmentioning

confidence: 99%

Online zinc reduction-sequential injection analysis for the determination of nitrogen species in extracts of riverine sediment

et al. 2017

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Background: The substitution of hazardous analytical reagents such as Cd with benign alternatives for chemical determination is one of the principles of green chemistry. An eco-friendly Zn reduction method for nitrate determination was developed to achieve this end. Methods: Online zinc reduction-sequential injection analysis (ZnR-SIA) protocol was developed for the determination of nitrogen (N) species in the Lagos Lagoon sediments by modification of some standard methods. Results: The novel application of boric acid-borate buffer employed in borate-buffered granular Zn reduction suppressed gas evolution from the Zn micro-column, making the Zn reduction adaptable to online use, unlike the frequently used ammonia-ammonium buffer. Further results showed that the sampling rate for the two-zone stack was 65 h

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“…Owing to the complex environmental matrix, one reason for FQs residues is the lack of reliable and effective analytical methods. A variety of analytical methods have been reported for the analysis of the FQs including HPLC-MS, HPLC-UV, HPLC-FLD [19][20][21][22][23][24], flow injection chemiluminescence [25,26], RRS [27], localized surface plasmon resonance (LSPR) [28], spectrophotometry [29], fluorimetry [30,31], electrochemistry [32,33], immunoassays [34,35] and luminescence [36], etc.…”

Section: Introductionmentioning

confidence: 99%

The dynamics of a novel method coupling high‐performance liquid chromatography with resonance Rayleigh scattering

Zhang

Peng

Liu

et al. 2011

J of Separation Science

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The dynamics of a novel method coupling high-performance liquid chromatography (HPLC) with resonance Rayleigh scattering (RRS) is presented in the paper. The method was employed in the detection of fluoroquinolones (FQs) of urine samples from healthy human beings, by forming ion-association complexes between the components separated from HPLC and [Ce(OH)(3) ](+) as the molecular recognition probe. The RRS signal was measured at λ(ex) =λ(em) =365 nm. It was applied to detect three FQs and obtained satisfactory results. The RRS spectral characteristics of the analytes and the kinetics of flow rate, proportion of organic phase, reaction time and the aggregation level of ion-association complexes were investigated, which provided a new basis for the development of the hyphenated techniques. It was established that the presence of HPLC-RRS would open up a new field in the determination of analytes in the absence of UV or fluorescence.

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Sequential injection technique applied to pharmaceutical analysis

Cited by 32 publications

References 47 publications

Automated Determination of Pharmaceutically and Biologically Active Thiols by Sequential Injection Analysis: A Review

Automated Determination of Pharmaceutically and Biologically Active Thiols by Sequential Injection Analysis: A Review

Online zinc reduction-sequential injection analysis for the determination of nitrogen species in extracts of riverine sediment

The dynamics of a novel method coupling high‐performance liquid chromatography with resonance Rayleigh scattering

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