Sequential Mycoplasma pneumoniae pneumonia and Chromobacterium violaceum skin abscess in a pediatric patient

Guo, Wei; Li, Iris Wai Sum; Li, Xi; Xu, Hua; Lu, Dongrong; Liu, Yue; Chen, Jiukai; Mok, Chris Ka Pun; Zhou, Yingchun

doi:10.3855/jidc.8878

Cited by 4 publications

(1 citation statement)

References 21 publications

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“…The isolates were found to be motile, Gram-negative, glucose-consuming bacteria with morphology and biochemistry aligned with Chromobacterium sp. The biochemical properties corresponded to Chromobacterium violceum isolated by Parajuli et al (2016) (31) and Guo et al (2017) (32) , also by Mazumder et al (2020) (33) in Bangladesh. All the isolates displayed similar results in our biochemical characterization, except some variations in their sugar fermentation and citrate reduction tests (Table 2), findings supported by a study conducted by Dall'Agnol et al (2008) (34) .…”

Section: Resultssupporting

confidence: 62%

Isolation and characterization of Chromobacterium violaceum and antibacterial activities of its metabolite violacein

Abedin,

Tarafdar,

Saha

et al. 2024

Dhaka Univ. J. Biol. Sci

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Violacein is a naturally-occurring bacterial secondary metabolite which is known to demonstrate a wide range of biological properties including antibacterial, antifungal, antiviral as well as anticancer and antitumor activities. Bacteria belonging to the genus Chromobacterium are the most studied microorganisms for violacein production. In this study, indigenous violacein-producing Chromobacterium violaceum was isolated from water and sediment samples of Bijaypur white clay hill lake, Netrokona, Bangladesh, and identified by biochemical and molecular characterization. After confirming the presence of the vioB gene in a polymerase chain reaction, crude violacein was purified from C. violaceum CV1 by ethanol extraction followed by filtration through 0.22 µm syringe filters. The partially-purified pigment exhibited significant antibacterial activity against three Gram-positive pathogens; Staphylococcus aureus, Streptococcus sp, and Listeria monocytogenes, with the later demonstrating the highest sensitivity. The bactericidal activity was more pronounced when combined with an antibiotic, thereby producing a drug-metabolite synergistic antibacterial activity. Dhaka Univ. J. Biol. Sci. 33(1): 109-119, 2024 (January)

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Section: Resultssupporting

confidence: 62%

Isolation and characterization of Chromobacterium violaceum and antibacterial activities of its metabolite violacein

Abedin,

Tarafdar,

Saha

et al. 2024

Dhaka Univ. J. Biol. Sci

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Chromobacterium violaceum infections in children: two case reports and literature review

Jiang,

Ren,

2024

Eur J Clin Microbiol Infect Dis

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Purpose Chromobacterium violaceum(C. violaceum) is a gram-negative bacterium that rarely infects humans, especially children. However, the mortality rate is high and there are no clear guidelines for treatment. The aim of this paper is to increase clinicians’ awareness of diseases caused by C. violaceum infections in children, to diagnose and treat them in a timely manner, to improve patient survival and to reduce mortality. Results We analysed the latest paediatric-related English language literature over the last 10 years and summarised the latest mechanisms of injury, susceptibility factors, adverse prognostic and mortality predictors, mortality rates, methods to reduce mortality, clinical manifestations, new diagnostic methods, therapeutic agents and directions for future drug development for C. violaceum. Conclusions Based on the available data, we conclude that the possibility of C. violaceum infection should be considered and diagnosed when cellulitis, septicaemia and visceral abscesses develop in children with a history of skin injury and exposure to stagnant water or soil. When clinicians strongly suspect that a child is infected with this bacterium, the recommended medication is ciprofloxacin if the child presents with severe illness. If the child has a non-severe condition, medications with relatively fewer side effects for children can be chosen, such as gentamicin, trimethoprim/ sulfamethoxazole, imipenem, and other drugs. The physician can then adjust the antimicrobial regimen based on the antimicrobial spectrum after obtaining the drug sensitivity results.

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Pediatric Fatal Chromobacterium violaceum in Tanzania: The First Documented Case

Bwire

Lema

Makala

et al. 2019

SN Compr. Clin. Med.

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Chomobacterium violaceum is a gram-negative bacteria, which inhabit soil or water and rarely causes disease in human. The first case of C. violaceum bacteria isolated from a 6-month-old male admitted at Muhimbili National Hospital, Tanzania, is reported. A patient had a high fever (39.2°C), vomiting with no history of convulsion, loss of consciousness, skin or joint infection, cough or difficulty in breathing, neither ear pain nor ear discharge. On admission, blood examination found no malaria parasites with normal urinalysis. Venous blood samples were taken for blood culture followed by empirical therapy with ceftriaxone 800 mg daily, intravenous paracetamol 125 mg stat then 125 mg 8 hourly was initiated. On the second day post-admission, the patient succumbed to septic shock before blood culture results were available. In conclusion, cultural and biochemical identification of a blood culture revealed C. violaceum infection.

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Sequential Mycoplasma pneumoniae pneumonia and Chromobacterium violaceum skin abscess in a pediatric patient

Cited by 4 publications

References 21 publications

Isolation and characterization of Chromobacterium violaceum and antibacterial activities of its metabolite violacein

Isolation and characterization of Chromobacterium violaceum and antibacterial activities of its metabolite violacein

Chromobacterium violaceum infections in children: two case reports and literature review

Pediatric Fatal Chromobacterium violaceum in Tanzania: The First Documented Case

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