Africa’s regional archives offer crucial records to explore the continent’s postcolonial past. Although these archives are often difficult to locate and access and are exposed to several challenges that might even threaten their existence, this article presents a solid case for reconsidering their importance. Recent trends, aptly labelled ‘postcolonial African archival pessimism’, have mainly pointed to problems and often to the limited accessibility of state archives in some regional and local contexts. This article instead engages with their potential, discussing four case studies in Benin, Cabo Verde, Ghana and Congo-Brazzaville. Results stemming from these case studies are brought into contact with wider debates on custodial cultures and the regional archives’ role in contemporary sub-Saharan Africa. The intention is to provide a more positive and empirically based overview of research possibilities at regional archives and ultimately to change the nature of our approach to these resources.