Serial and prolonged EEG monitoring in anti-N-Methyl-d-Aspartate receptor encephalitis

EEG extreme delta brush: An ictal pattern in patients with anti-NMDA receptor encephalitis

“…Some authors using depth electrode recordings have confirmed their ictal nature in some patients [12]. Other authors rule out their ictal nature on the basis of an absence of voltage or field evolution or nonresponse to BZDs [13][14][15]. Also, depth electrode recordings have determined their nonictal nature in one patient with anti-NMDAr encephalitis [16].…”

Extreme Delta Brushes in Pediatric Anti-N-Methyl-DAspartate Receptor Encephalitis

“…Extreme delta brushes in childhood were described in only a few studies [6,10,11]. In one pediatric series, the frequency of this EEG pattern was only 5% [10].…”

“…Slow, rhythmic delta activity predominates in the catatonic-like stage. This activity is not associated with abnormal movements and does not respond to antiepileptic drugs [3,6].…”

Nouveaux outils de neuromonitorage

“…Le monitorage vidéo-EEG continu peut être une aide intéressante, en permettant de limiter l'escalade thé-rapeutique et les sédations inutiles. Ces enregistrements continus ont permis de mettre en évidence des marqueurs EEG pronostiques (extrem delta brush) et des anomalies paroxystiques (activités delta rythmiques généralisées) [84,85] qui ne doivent pas conduire à majorer les traitements antiépileptiques (Fig. 4).…”