2010
DOI: 10.1002/ccd.22618
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Series of transcatheter valve‐in‐valve implantations in high‐risk patients with degenerated bioprostheses in aortic and mitral position

Abstract: With growing need for reoperative valve replacement in elderly patients with disproportional operative risks, transcatheter valve-in-valve implantation in aortic and mitral position offers an alternative treatment option. Although valve function after transcatheter implantation was good in all patients, two high risk patients died in the postoperative period due to their significant comorbidities, underscoring the bail-out character of this procedure.

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Cited by 101 publications
(64 citation statements)
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“…To date, several cases of transcatheter mitral valve-in-valve implantations have been reported, but only 1 case of transapical valve-in-ring implantation has been reported. [1][2][3][4] The present report confirms the feasibility and effectiveness of such transcatheter mitral interventions and the ability of the Sapien valve to be sewed in an asymmetrical annuloplasty ring as previously observed 1 and demonstrated here. Questions about valve-in-ring implantation concern the size, the deformability, and the asymmetrical geometry of the ring.…”
Section: Discussionsupporting
confidence: 87%
See 1 more Smart Citation
“…To date, several cases of transcatheter mitral valve-in-valve implantations have been reported, but only 1 case of transapical valve-in-ring implantation has been reported. [1][2][3][4] The present report confirms the feasibility and effectiveness of such transcatheter mitral interventions and the ability of the Sapien valve to be sewed in an asymmetrical annuloplasty ring as previously observed 1 and demonstrated here. Questions about valve-in-ring implantation concern the size, the deformability, and the asymmetrical geometry of the ring.…”
Section: Discussionsupporting
confidence: 87%
“…Another unsuccessful attempt through a transatrial route was performed, and all other cases were achieved through the transapical route. 2,3 The transseptal route has several advantages, including being less invasive, carrying minimal risk of vascular complications, and being compatible with local anesthesia. However, several precautions should be considered: (1) Expertise in transseptal catheterization is required, (2) the distance between the septal puncture site and the mitral valve must be sufficient to allow complete deployment of the balloon in the left atrium (a high and posterior transseptal puncture site may be considered in this particular context), and (3) the positioning may be easier and more stable with the transapical route.…”
Section: Discussionmentioning
confidence: 99%
“…8 -10 In recent years, several reports have suggested that the off-label use of TAVR within failed surgically inserted bioprosthetic valves (valve-in-valve [VIV]) is technically feasible. [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] However, all previous reports evaluating the VIV approach have included a small number of cases and are limited in providing measures of efficacy and safety. High postprocedural gradients and several potentially life-threatening complications, such as ostial coronary obstruction, were only reported anecdotally, and there was no comparison between different devices possibly applicable for VIV.…”
Section: Editorial See P 2280 Clinical Perspective On P 2344mentioning
confidence: 99%
“…7,[20][21][22] A Canadian registry (n=24) was soon followed by an Italian registry (n=25), 2 German registries (n=20, n=47), and numerous other small case series and isolated case reports documenting favorable outcomes. 7,8,[23][24][25][26][27][28][29][30][31] The Global Valve-in-Valve Registry, an industry-independent collaboration, was introduced in 2010 to collate this increasing but widely distributed experience.…”
Section: The Vinv Procedures Clinical Experiencementioning
confidence: 99%