The purpose of this research work is to provide a measurement instrument, through the validation of a proposed scale, to determine the relevant factors that affect the motivation of university students, and that can be used as anticipatory indicators of personal entrepreneurship to achieve educational and work success. To carry it out, exploratory and confirmatory factor analyses have been carried out, based on the principal components’ method, which have been validated through the usual model fit measures in the literature, considering an analysis of reliability and reliability of the measurement instrument. To obtain this purpose, a sample of the university population was selected, through a simple random sampling, considering heterogeneity of courses, subjects, areas, and teaching modalities, of 596 individuals, with a higher percentage of women compared to men, as can be seen from the total number of enrolled in university degrees in the Spanish education system. The scale proved to have good psychometric properties, obtaining good internal consistency and validity. Among the main findings, we can highlight several dimensions for motivation, for instance, emotional self-management and adversity management; and learning strategies, such as: active self-management of study material, study management and self-management of effort, among others. In conclusion, a scale has been validated to determine which dimensions should be considered to promote student motivation as a method of personal entrepreneurship, and which can be used by educational authorities to propose extracurricular training that affects the improvement of students' competence, both in academic and emotional management. The dataset was analyzed using exploratory and confirmatory factor analysis.