Sero-Epidemiological Study of Human Hydatidosis in Semnan and Sorkheh, Semnan Province, Iran

Abstract

Background: To determine the seroprevalence of human cystic echinococcosis/hydatidosis which is one of the most important zoonotic diseases by ELISA using native antigen B in Semnan and Sorkheh, Semnan province, Iran, where no significant information about human infection exists.
 Methods: Overall, 957 human serum samples were randomly prepared from Semnan, Sorkheh, and its 13 surrounding villages in different seasons from 2017 to 2018. Antigen B was prepared from native hydatid cyst fluid of domestic sheep. All serum samples were evaluated by ELISA while the suspected cases were rechecked. The cut-off was calculated as the X̄±2SD.
 Results: Overall, 48(5%) out of 957 (422 males and 535 females) were positive for hydatidosis. The seropositivity based on sex showed 20(2.1%) out of 422 in males and 28(2.9%) out of 535 in females. The distribution of seropositive samples based on residence area showed 41 (4.3) out of 882 in urban and 7 (0.7) out of 75 in rural areas. The highest seroprevalence cases was among housewives (2.1%) followed by employers (1.5%). Based on education, source of drinking water, and age groups the highest seropositivity was observed in high school and less, in the plumping water consumers, and 50 to 59 yr old age group, respectively. There was a significant difference between seropositivity with occupation, literacy, and age group (P<0.05). Semnan with 4% seropositivity had the highest prevalence followed by Sorkheh, county.
 Conclusion: High prevalence of the disease in this area emphasizes the importance of increasing people's awareness about hydatidosis.

Investigating outbreaks caused by foodborne diseases and determining common bacterial agents that cause them in Kurdistan province

“…In a study, on all outbreaks caused by food in Semnan Province, it has shown that the prevalence rate was higher in women than in children and men (46%). The frequency of outbreaks in 24-44 years was observed more than in other groups (31.57%) [12][13][14][15][16][17].…”

“…Foodborne diseases are one of the most important problems, especially in developing countries, and they are one of the main factors in morbidity and mortality all over the world. Food is an important carrier in the transmission of microorganisms to humans, and among these microorganisms, Salmonella is still the main cause of foodborne diseases in the pathogenesis of humans throughout the world [13][14][15]31].…”

Comparison of Native Hydatid Cyst Fluid (HCF), Lyophilized HCF, Antigen B (AgB) and Lyophilized AgB (LAgB) Originated from Echinococcus granulosus Sensu Stricto for Sero-Diagnosis of Active, Transitional and Inactive Human Liver Cystic Echinococcosis

“…Different antigens including native, semi purified or recombinant have been used for CE diagnosis ( 16 , 19 , 25 – 29 ). They have been used for both diagnostic and sero-epidemiological purposes ( 26 , 30 – 34 ). Although, lyophilized antigens have been used in limited studies ( 21 , 22 ), but the validity of lyophilized HCF and AgB has not been evaluated and compared.…”