Sero-prevalence of West Nile virus in north-eastern Italy

Pierro, Anna; Gaibani, Paolo; Cavrini, Francesca; Manisera, C.; Rossini, Giada; Landini, M.P.; Sambri, Vittorio

doi:10.1016/j.ijid.2010.02.1952

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As recently stressed by reports from hyperendemic areas [ 10 , 17 , 54 ], including the occupational report by Atim et al [ 54 ], a radical paradigm shift is, therefore, conceivable when pondering the CCHF-associated actual burden of disease. Similar to other vector-borne diseases such as West Nile Fever [ 66 , 67 , 68 , 69 , 70 , 71 , 72 ], Dengue [ 73 , 74 , 75 , 76 ], and Tick-Borne Encephalitis [ 77 , 78 , 79 , 80 , 81 ], CCHF should be understood as a relatively rare occurrence following CCHFV infection, while majority of cases either go unnoticed or misunderstood as “summer flu” [ 82 ]. Far from dismissing the potential significance of this pathogen, a more appropriate appraisal of CCHFV in the evolving landscape of vector-borne diseases underlines the role of occupational physicians and medical surveillance in occupational settings as instrumental in improving our appropriate understanding of the CCHF epidemiology [ 83 , 84 , 85 ].…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of Crimean Congo Hemorrhagic Fever Virus in Occupational Settings: Systematic Review and Meta-Analysis

Riccò,

Baldassarre,

Corrado

et al. 2023

TropicalMed

View full text Add to dashboard Cite

Crimean Congo Hemorrhagic Fever (CCHF) Virus can cause a serious human disease, with the case fatality ratio previously estimated to be 30–40%. Our study summarized seroprevalence data from occupational settings, focusing on the following occupational groups: animal handlers, abattoir workers, farmers, healthcare workers, veterinarians, rangers, and hunters. Systematic research was performed on three databases (PubMed, EMBASE, MedRxiv), and all studies reporting seroprevalence rates (IgG-positive status) for CCHF virus were retrieved and their results were reported, summarized, and compared. We identified a total of 33 articles, including a total of 20,195 samples, i.e., 13,197 workers from index occupational groups and 6998 individuals from the general population. Pooled seroprevalence rates ranged from 4.751% (95% confidence intervals (95% CI) 1.834 to 11.702) among animal handlers, to 3.403% (95% CI 2.44 to 3.932) for farmers, 2.737% (95% CI 0.896 to 8.054) among rangers and hunters, 1.900% (95% CI 0.738 to 4.808) for abattoir workers, and 0.644% (95% CI 0.223–1.849) for healthcare workers, with the lowest estimate found in veterinarians (0.283%, 95% CI 0.040–1.977). Seroprevalence rates for abattoir workers (odds ratio (OR) 4.198, 95% CI 1.060–16.464), animal handlers (OR 2.399, 95% CI 1.318–4.369), and farmers (OR 2.280, 95% CI 1.419 to 3.662) largely exceeded the official notification rates for CCHF in the general population. CCHF is reasonably underreported, and pooled estimates stress the importance of improving the adherence to personal protective equipment use and appropriate preventive habits.

show abstract

Section: Discussionmentioning

confidence: 99%

Seroprevalence of Crimean Congo Hemorrhagic Fever Virus in Occupational Settings: Systematic Review and Meta-Analysis

Riccò,

Baldassarre,

Corrado

et al. 2023

TropicalMed

View full text Add to dashboard Cite

show abstract

“…This design was motivated by the lack of similar studies on medical professionals, and particularly from endemic areas of continental Europe. Even though WNV has progressively become an endemic pathogen to Northern Italy, and particularly to the Po River Valley [27,28,30,42,[70][71][72][73], the actual understanding of WNV infections among Italian healthcare providers has been only scarcely inquired. Shortly before the inception of SARS-CoV-2 pandemic, a KAP study on 174 Italian occupational physicians [48] identified a relatively satisfying understanding of WNV infections and their preventive measures, still stressing the extensive underestimation of their actual occurrence in the general population and their severity as well.…”

Section: Discussionmentioning

confidence: 99%

West Nile Virus Infection: A Cross-Sectional Study on Italian Medical Professionals during Summer Season 2022

et al. 2022

View full text Add to dashboard Cite

West Nile virus (WNV) has progressively endemized in large areas of continental Europe, and particularly in Northern Italy, in the Po River Valley. During summer season 2022, Italy experienced an unprecedented surge in incidence cases of WNV infections, including its main complications (West Nile fever (WNF) and West Nile neuroinvasive disease (WNND)). As knowledge, attitudes, and practices (KAP) of medical professionals may be instrumental in guaranteeing a prompt diagnosis and an accurate management of incident cases, we performed a cross-sectional study specifically on a sample of Italian medical professionals (1 August 2022–10 September 2022; around 8800 potential recipients). From a total of 332 questionnaires (response rate of 3.8%), 254 participating medical professionals were eventually included in the analyses. Knowledge status of participants was unsatisfying, as most of them exhibited knowledge gaps on the actual epidemiology of WNV, with similar uncertainties on the clinical features of WNF and WNND. Moreover, most of participants substantially overlooked WNV as a human pathogen when compared to SARS-CoV-2, TB, and even HIV. Interestingly, only 65.4% of respondents were either favorable or highly favorable towards a hypothetical WNV vaccine. Overall, acknowledging a higher risk perception on WNV was associated with individual factors such as reporting a seniority ≥ 10 years (adjusted odds ratio [aOR] 2.39, 95% Confidence interval [95%CI] 1.34 to 4.28), reporting a better knowledge score (aOR 2.92, 95%CI 1.60 to 5.30), having previously managed cases of WNV infections (aOR 3.65, 95%CI 1.14 to 14.20), being favorable towards a hypothetic vaccine (aOR 2.16, 95%CI 1.15 to 4.04), and perceiving WNV infections as potentially affecting daily activities (aOR 2.57, 95%CI 1.22 to 5.42). In summary, substantial knowledge gaps and the erratic risk perception collectively enlighten the importance and the urgency for appropriate information campaigns among medical professionals, and particularly among frontline personnel.

show abstract

Sero-prevalence of West Nile virus in north-eastern Italy

Cited by 2 publications

References 0 publications

Seroprevalence of Crimean Congo Hemorrhagic Fever Virus in Occupational Settings: Systematic Review and Meta-Analysis

Seroprevalence of Crimean Congo Hemorrhagic Fever Virus in Occupational Settings: Systematic Review and Meta-Analysis

West Nile Virus Infection: A Cross-Sectional Study on Italian Medical Professionals during Summer Season 2022

Contact Info

Product

Resources

About