Sero-surveillance of measles amongst vaccinated and non-vaccinated children: An age stratified population based survey in Pakistan

Channa, Rafique Ahmad; Hussain, Shahzad; Kanher, Nisar Ahmad; Malik, Farnaz; Memon, MazharUllah; Mahmood, Sajid; Yasin, Fahdiya; Wajid, Amina; Shafaat, Shazia; Mahmood, Rashid; Parveen, Ghazala; Ahmad, Safia; Ismail, Muhammad

doi:10.5897/ajpp11.610

Cited by 1 publication

(2 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, the prevalence of antibodies increased with age, which is consistent with previous findings [16,35,36]. This might be due to the vaccination schedule or changes in maturing immune systems [26].…”

Section: Discussionsupporting

confidence: 92%

“…This might be due to the vaccination schedule or changes in maturing immune systems [26]. A study in Pakistan found that the levels of the measles-specific IgG antibody increased from 60.0% to 84.62% in children aged 9 months to 5 years [36]. Those IgG levels are lower than those in the present study, which may be related to the poor living conditions or nutritional status in the Pakistani sample.…”

Section: Discussioncontrasting

confidence: 65%

See 1 more Smart Citation

Seroprevalence of Measles Antibodies and Predictors for Seropositivity among Chinese Children

Wang

Hui

et al. 2017

IJERPH

View full text Add to dashboard Cite

Background: Supplementary measles immunization has been implemented since 2010 throughout China, yet few studies have reported its effect in the northwest regions. Methods: A cross-sectional study was conducted among children aged 2 to 4 years old (n = 755) from February to September 2014 in 25 towns of Qian County, Shaanxi Province. Blood samples were analyzed for measles antibodies using enzyme-linked immunosorbent immunoglobulin G (IgG) assays. Socio-demographic factors were assessed by questionnaire. Data on vaccine dose were collected from town medical records. Univariate and logistic regression analyses were used to determine factors associated with measles antibody seropositivity. Results: Measles antibody seroprevalence was 91.13% (95% CI: 89.52–92.83) in our sample. Compared with children whose mother’s highest education was primary school, seroprevalence was higher in children whose maternal education was middle school (adjusted OR: 1.4, 95% CI: 0.7–2.8), high school (adjusted OR: 2.4, 95% CI: 1.3–7.7), and college/university (adjusted OR: 2.9, 95% CI: 1.2–9.3). Vaccine dose was positively associated with seropositivity. Conclusions: Measles seroprevalence is high in China and is associated with the mother’s education and vaccine dose.

show abstract