Seroepidemiological survey of Border Disease (BD) in Syrian Awassi sheep

Tabbaa, Darem; Giangaspero, Massimo; Nishikawa, Hiroaki

doi:10.1016/0921-4488(94)00030-b

Cited by 2 publications

(2 citation statements)

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“…The seasonal migration of flocks and the use of communal pastures for grazing make the direct or indirect exposure to other species possible, including free-living ruminants [ 4 , 15 ]. In another study carried out in Syria, it has been reported that transhumant flocks, especially those travelling long distances, have a significantly higher seroprevalence with an increase of 14% compared to sedentary flocks or those moving on short distances [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of border disease virus and other pestiviruses in sheep in Algeria and associated risk factors

et al. 2018

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BackgroundBorder disease virus (BDV) is a pestivirus responsible for significant economic losses in sheep industry. The present study was conducted between 2015 and 2016 to determine the flock seroprevalence of the disease in Algeria and to identify associated risk factors. 56 flocks from nine departments were visited and 689 blood samples were collected from adult sheep between 6 and 24 months of age (n = 576) and from lambs younger than 6 months (n = 113). All samples were tested by RT-PCR as well as by Ag-ELISA, to detect Persistently Infected (PI) animals. Serum samples from adults were tested by Ab-ELISA (Enzyme Linked Immuno-Sorbent Assay), to detect specific antibodies against pestivirus and 197 of them were further characterized by VNT (virus neutralization test) for the detection of neutralizing antibodies specific for BDV and for Bovine virus diarrhea virus (BVDV-1 and BVDV-2).ResultsNo PI animals were found among the 689 sheep tested. 144/197 sera were positive in VNT for BDV, and 2 sera were strongly positive BVDV-2. Fifty-five flocks (98%) had at least one seropositive animal and the apparent within-flock seroprevalence was estimated to be 60.17% (95% C.I.: 52.96–66.96). The true seroprevalence based on estimated sensitivity and specificity of the Ab-ELISA was 68.20% (95% C.I.; 60.2–76.3). Several risk factors were identified as linked to BDV such as climate, landscape, flock management and presence of other ruminant species in the farm.ConclusionThese high seroprevalence rates suggest that BDV is widespread and is probably endemic all over the country. Further studies are needed to detect and isolate the virus strains circulating in the country and understand the distribution and impact of pestiviruses in the Algerian livestock.Electronic supplementary materialThe online version of this article (10.1186/s12917-018-1666-y) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Seroprevalence of border disease virus and other pestiviruses in sheep in Algeria and associated risk factors

et al. 2018

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“…Pestivirus infections in small ruminants are widespread worldwide with a wide range of seroprevalences depending on the management of animal husbandry (Barlow, 1990;Loken et al, 1991;Tabbaa et al, 1995;Nettleton und Entrican, 1995;Zaghawa, 1998;Tegtmeier et al, 2000;Graham et al, 2001;Celedon et al, 2001;O'Neill et al, 2004;Berriatua et al, 2004;Krametter-Froetscher et al, 2006;Okur-Gumusova et al, 2006). On Swiss sheep breeding farms, a seroprevalence of 20 % was found in a representative sample of sera collected in 1993 (Schaller…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence and characterization of pestivirus infections in small ruminants and new world camelids in Switzerland

Danuser

Vogt²,

Kaufmann³

et al. 2009

Schweizer Archiv für Tierheilkunde

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The seroprevalence of pestivirus infections in small ruminants and new world camelids in Switzerland was determined. In 5'059 sera of sheep from 382 herds, 503 sera of goats from 54 herds and 109 sera of alpacas and lamas from 53 herds, population prevalences of 16.1% (sheep), 25.4% (goats) and 4.6% (new world camelids), respectively, were found. In order to determine the source of infection, the serological reactions were further characterized by cross-neutralization against two pestiviruses representing the genotypes BVDV (Bovine Virus Diarrhea Virus)-1 and BDV (Border Disease Virus)-1. Based on the ratio of respective antibody titres, 56.1% of the infections in sheep were induced by a BDV-1, 12.9% by a BVDV-1 and 31.0% by an unresolved pestivirus. In goats, the corresponding proportions were 23.4%, 10.2% and 66.4%, respectively. In Alpacas and Lamas, the source of infection of 1 animal was BDV-1 and that of 4 seropositive animals remained unresolved. In view of the phylogenetic relationship between pestiviruses, the unresolved source of infection is most probably attributable to other pestivirus genotypes circulating in small ruminants and new world camelids. Due to the predominance of pestiviral genotypes other than BVDV-1, the risk of transmission of BVDV from persistently infected small ruminants and new world camelids to cattle appears to be moderate, apart from close direct contact in mixed animal husbandry, communal pasturing and grazing in the Alps.

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Seroepidemiological survey of Border Disease (BD) in Syrian Awassi sheep

Cited by 2 publications

References 3 publications

Seroprevalence of border disease virus and other pestiviruses in sheep in Algeria and associated risk factors

Seroprevalence of border disease virus and other pestiviruses in sheep in Algeria and associated risk factors

Seroprevalence and characterization of pestivirus infections in small ruminants and new world camelids in Switzerland

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