Seroepidemiology of foot and mouth disease (FMD) virus non-structural protein (NSP) antibodies in the livestock of Oman

Hussain, Muhammad Hammad; Body, Mohammed; Al-Subhi, A H A; Al-Senaidi, N Y A; El-Tahir, Hatim Ali; Mansoor, Muhammad; Al-Zadjali, Mohammed Somar; Al-Habsi, Saif; Aluahmadi, Sheikha Saif Rashid; Al-Subhi, Ruqiya Salem Nasser; Al-Beloushi, Muzna Khalifa Ismail; Al-Riyami, Bushra Salim Thani; Al-Rawahi, Abdulmajeed

doi:10.1016/j.actatropica.2019.105106

Cited by 9 publications

(4 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Further, there was high sero-prevalence in animals whose production type was not identified hence the need for further investigation of sero-prevalence between the production types. The proportion of herds with at least one animal sero-positive for FMD (herd prevalence) was high at 77.6% similar to 74.7% reported by Ahmed et al [ 41 ] in Ethiopian cattle but higher than that in the reports of Megersa et al [ 64 ] in southern Ethiopian cattle and Hussain et al [ 65 ] in Omani cattle with sero-prevalence of 48.1% and 55.2%, respectively. This comparison of SR herds and cattle herds is relevant given possible transmission from cattle to SR.…”

Section: Discussionsupporting

confidence: 72%

Epidemiological study on foot-and-mouth disease in small ruminants: Sero-prevalence and risk factor assessment in Kenya

Chepkwony¹,

Gitao

Muchemi

et al. 2021

PLoS ONE

View full text Add to dashboard Cite

Foot-and-mouth disease (FMD) is endemic in Kenya affecting cloven-hoofed ruminants. The epidemiology of the disease in small ruminants (SR) in Kenya is not documented. We carried out a cross-sectional study, the first in Kenya, to estimate the sero-prevalence of FMD in SR and the associated risk factors nationally. Selection of animals to be sampled used a multistage cluster sampling approach. Serum samples totaling 7564 were screened for FMD antibodies of non-structural-proteins using ID Screen® NSP Competition ELISA kit. To identify the risk factors, generalized linear mixed effects (GLMM) logistic regression analysis with county and villages as random effect variables was used. The country animal level sero-prevalence was 22.5% (95% CI: 22.3%-24.3%) while herd level sero-prevalence was 77.6% (95% CI: 73.9%-80.9%). The risk factor that was significantly positively associated with FMD sero-positivity in SR was multipurpose production type (OR = 1.307; p = 0.042). The risk factors that were significantly negatively associated with FMD sero-positivity were male sex (OR = 0.796; p = 0.007), young age (OR = 0.470; p = 0.010), and sedentary production zone (OR = 0.324; p<0.001). There were no statistically significant intra class correlations among the random effect variables but interactions between age and sex variables among the studied animals were statistically significant (p = 0.019). This study showed that there may be widespread undetected virus circulation in SR indicated by the near ubiquitous spatial distribution of significant FMD sero-positivity in the country. Strengthening of risk-based FMD surveillance in small ruminants is recommended. Adjustment of husbandry practices to control FMD in SR and in-contact species is suggested. Cross-transmission of FMD and more risk factors need to be researched.

show abstract

Section: Discussionsupporting

confidence: 72%

Epidemiological study on foot-and-mouth disease in small ruminants: Sero-prevalence and risk factor assessment in Kenya

Chepkwony¹,

Gitao

Muchemi

et al. 2021

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…ose differences of figures of prevalence reported by different scholars might be due to variation in a management system, free movement of cloven-hoofed animals, unequal distribution of vaccine through the country, intervention and agroclimatic condition, and presence of communal grazing and watering in the current study area. e 74.7% seropositivity at the herd level in this study was higher than the reports of Megersa et al [31] in southern Ethiopia and Hussain et al's study [35] in Oman with seroprevalence of 48.1% and 55.2%, respectively. e higher e multivariable logistic regression model of risk factors analysis indicated that districts, breed, and animal composition in herds had a significant association with seroprevalence of FMD and hence are independent predictors (p < 0.05).…”

Section: Discussioncontrasting

confidence: 64%

Seroprevalence and Associated Risk Factors of Foot and Mouth Disease in Cattle in West Shewa Zone, Ethiopia

Ahmed

Megersa

Mulatu

et al. 2020

Veterinary Medicine International

View full text Add to dashboard Cite

Foot and mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals and one of the endemic diseases in Ethiopia. The study was aimed to estimate the seroprevalence and to assess associated risk factors of foot and mouth disease seroprevalence in West Shewa Zone. A total of 384 sera samples were collected from randomly selected cattle and tested using ELISA for antibodies against nonstructural proteins of foot and mouth disease viruses based on IDEXX FMD Multispecies Ab Test (IDEXX Laboratories Inc, USA). The seroprevalence of foot and mouth disease in West Shewa Zone was found to be 40.4% (95% CI: 35.46–45.27) at an animal and 74.7% (95% CI: 65.58–83.85) at the herd level. Multivariable logistic regression analysis indicated that districts, breed, and animal composition were the potential risk factors of FMD seropositivity. Accordingly, cattle found in Abuna Ginde Beret (odds ratio (OR): 9.1, 95% CI: 2.4–34.1, p=0.001), Cheliya (OR: 8.8, 95% CI: 2.5–31.3, p=0.001), Bako Tibe (OR: 7.6, 95% CI: 2.1–28.3, p=0.002), Tokekutaye (OR: 5.8, 95% CI: 1.7–19.5, p=0.004), and Jeldu (OR: 5.3, 95% CI: 1.3–21.5, p=0.020) districts were more at risk to be infected with FMD than cattle from Ambo. The odds of FMD seropositivity was significantly higher in cattle kept with small ruminants (OR: 2.1, 95% CI: 1.3–3.3, p=0.003) than cattle alone. The analysis also revealed that the odds of seropositivity were 6 times higher in crossbred compared with local cattle (p=0.003). The current study found high seroprevalence of FMD in West Shewa Zone. Therefore, cattle should be vaccinated regularly after the identification of specific FMD serotypes circulating in the study area.

show abstract

“…Whereas buffaloes FMDV strains genetically distinct from the strains obtained from cattle [44], the present study strengthens FMD surveillance in buffaloes as they could pose a potential risk of virus transmission to cattle. From a broader perspective, despite the strict control policies and quarantine measures at the borders, similar results to NSPs antibodies of FMDV that obtained in Egypt were recorded in Libya (19.0% [45], Sudan (25.0%) [46], Ethiopia (24.2%) [47], Saudi Arabia (25.0%) [48], Oman (26.8%) [49], and India (27.7%) [21], indicating a risk of transboundary transmission of new topotypes/ lineages of the virus. Regional cooperation including data/information and applied control measures on the FMD outbreaks is required [50].…”

Section: Discussionsupporting

confidence: 70%

January-2020

2020

Vet World

View full text Add to dashboard Cite

Aim: The present study was aimed to investigate the epidemic situation of foot-and-mouth disease (FMD) in Egypt from 2016 to 2018 based on the detection of FMD virus (FMDV) in carrier or previously infected animals, by determination of antibodies against non-structural protein (NSP), implementation a pilot study on circulating FMDV serotypes and assure the efficacy of locally produced inactivated trivalent vaccine. Materials and Methods:A total of 1500 sera were collected from apparent healthy vaccinated cattle and buffaloes from three Egyptian geographical sectors, representing ten governorates. Determination of FMD antibodies against NSP was carried out using 3ABC enzyme-linked immunosorbent assay (ELISA) test. Serotyping of the circulating FMDV and assure the vaccine efficacy was performed using solid-phase competitive ELISA. Results:The 3ABC ELISA test revealed 26.4% and 23.7% positive for FMDV-NSP antibodies in cattle and buffalo sera, respectively. The highest positivity was in Delta Sector among both cattle 42.3% and buffaloes 28.8%. Serotyping of FMDV-positive NSP sera in El-Qalyubia Governorate for the circulating FMDV serotypes O, A, and Southern African Territories (SAT) 2 was 52.2%, 17.4%, and 30.4% in cattle and 31.8%, 27.3%, and 40.9% in buffaloes, respectively. The overall protection level due to the vaccination program was 62.1 and 60.9% in cattle and buffaloes, respectively, while the protective level of the FMDV serotypes O, A, and SAT2 included in the inactivated trivalent vaccine was 73.9, 84.6, and 63.8% in cattle and 72.3, 82.3, and 63.5% in buffaloes, respectively. Conclusion:The present study recommended full determination for the immunogenic relationship between the vaccine strains and the field strains to attain maximum protection against the circulating viruses.

show abstract

Seroepidemiology of foot and mouth disease (FMD) virus non-structural protein (NSP) antibodies in the livestock of Oman

Cited by 9 publications

References 21 publications

Epidemiological study on foot-and-mouth disease in small ruminants: Sero-prevalence and risk factor assessment in Kenya

Epidemiological study on foot-and-mouth disease in small ruminants: Sero-prevalence and risk factor assessment in Kenya

Seroprevalence and Associated Risk Factors of Foot and Mouth Disease in Cattle in West Shewa Zone, Ethiopia

January-2020

Contact Info

Product

Resources

About