Serological and clinical surveillance studies to validate reported foot-and-mouth disease free status in Tsirang district of Bhutan

Dukpa, Kinzang; Robertson, Ian D.; Ellis, T.M.

doi:10.1016/j.prevetmed.2011.10.015

Cited by 4 publications

(6 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ELISAs based on anti NSP antibodies are extensively used in surveys aimed at estimating the level of exposure to FMD of livestock as a part of endemic and post-epidemic surveillance programs (Ayelet et al, 2012;Chen et al, 2011;Chung et al, 2003;Dukpa et al, 2012). Yet, estimation of the longevity of anti NSP antibodies and sensitivity of detection of the anti NSP antibodies in cattle naturally exposed to FMDV, based on ELISA tests, were rarely studied to date.…”

Section: Discussionmentioning

confidence: 99%

The longevity of anti NSP antibodies and the sensitivity of a 3ABC ELISA – A 3 years follow up of repeatedly vaccinated dairy cattle infected by foot and mouth disease virus

Elnekave

Shilo

Gelman³

et al. 2015

Veterinary Microbiology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

The longevity of anti NSP antibodies and the sensitivity of a 3ABC ELISA – A 3 years follow up of repeatedly vaccinated dairy cattle infected by foot and mouth disease virus

Elnekave

Shilo

Gelman³

et al. 2015

Veterinary Microbiology

View full text Add to dashboard Cite

“…Although many questions still remain to be resolved in the actual application of these methods to human diseases (see below and ref. 37 ), the work presented here, together with results from an analysis carried out by Dukpa et al 38 with respect to validating the reported status of a district in Bhutan being free from foot-and-mouth disease, point to the potential power of applying these non-zero prevalence thresholds for guiding the making of defensible evidence-based intervention stopping decisions in disease control programmes.…”

Section: Discussionmentioning

confidence: 54%

“…On a final note, we highlight that although our modelling approach was developed for supporting decision-making for the two diseases studied here, the developed framework is flexible and can be easily made specific for other parasitic diseases and management goals. This will be the case whether or not mathematical models that allow estimation of breakpoint transmission thresholds exist for these diseases, as in the absence of such predictions traditional FFI calculations based on zero survey data could still be used 38 . We are currently evaluating such enhancements, particularly with regard to the spatio-temporal and economic extensions required for (1) facilitating effective area-wide disease freedom assessments and (2) optimizing economically sound infection thresholds applicable to different settings, in our laboratory.…”

Section: Discussionmentioning

confidence: 99%

Substantiating freedom from parasitic infection by combining transmission model predictions with disease surveys

et al. 2018

View full text Add to dashboard Cite

Stopping interventions is a critical decision for parasite elimination programmes. Quantifying the probability that elimination has occurred due to interventions can be facilitated by combining infection status information from parasitological surveys with extinction thresholds predicted by parasite transmission models. Here we demonstrate how the integrated use of these two pieces of information derived from infection monitoring data can be used to develop an analytic framework for guiding the making of defensible decisions to stop interventions. We present a computational tool to perform these probability calculations and demonstrate its practical utility for supporting intervention cessation decisions by applying the framework to infection data from programmes aiming to eliminate onchocerciasis and lymphatic filariasis in Uganda and Nigeria, respectively. We highlight a possible method for validating the results in the field, and discuss further refinements and extensions required to deploy this predictive tool for guiding decision making by programme managers.

show abstract

“…A study by Dukpa et al. (Dukpa et al., ) reported freedom from disease in one district of Bhutan based on non‐structural protein testing. The authors propose the feasibility of FMD progressive control using zoning strategies, given the heterogeneity of viral circulation in different areas of the country.…”

Section: Endemic Pools In Asiamentioning

confidence: 99%

Review of the Global Distribution of Foot-and-Mouth Disease Virus from 2007 to 2014

Brito

Rodrı́guez

Hammond

et al. 2015

Transbound Emerg Dis

223

212

View full text Add to dashboard Cite

Foot-and-mouth disease (FMD) virus affects livestock worldwide. There are seven different serotypes, each with a diversity of topotypes, genetic lineages and strains. Some lineages have different properties that may contribute to sporadic spread beyond their recognized endemic areas. The objective of this study was to review the most significant FMD epidemiological events that took place worldwide between 2007 and 2014. Severe epidemics were caused by FMD virus (FMDV) lineage O/Asia/Mya-98 in Japan and South Korea in 2010, both previously free of disease. In India, where FMD is endemic, the most important event was the re-emergence of lineage O/ME-SA/Ind-2001 in 2008. Notably, this lineage, normally restricted to India, Bangladesh, Nepal and Bhutan, was also found in Saudi Arabia and Libya in 2013 and has caused several outbreaks in Tunisia and Algeria in 2014-2015. In January 2011, FMDV-positive wild boars were found in Bulgaria, where the disease last occurred in 1996, followed by 12 outbreaks in livestock infected with FMDV O/ME-SA/PanAsia2. In 2012, FMDV SAT2 caused outbreaks in Egypt and the Palestinian Autonomous Territories. Another significant event was the emergence of FMDV Asia1 Sindh-08 in the Middle East. In South America, one outbreak of FMDV serotype O, topotype Euro-SA was reported in Paraguay in 2011, which was recognized as FMD-free with vaccination at the time. Lessons learned from past events, point out the need for an integrated strategy that comprises coordinated global and regional efforts for FMDV control and surveillance. Specific local characteristics related to host, environment and virus that condition FMD occurrence should be carefully considered and incorporated to adapt appropriate strategies into local plans. In this review, we compiled relevant epidemiological FMD events to provide a global overview of the current situation. We further discussed current challenges present in different FMD areas.

show abstract

Serological and clinical surveillance studies to validate reported foot-and-mouth disease free status in Tsirang district of Bhutan

Cited by 4 publications

References 30 publications

The longevity of anti NSP antibodies and the sensitivity of a 3ABC ELISA – A 3 years follow up of repeatedly vaccinated dairy cattle infected by foot and mouth disease virus

The longevity of anti NSP antibodies and the sensitivity of a 3ABC ELISA – A 3 years follow up of repeatedly vaccinated dairy cattle infected by foot and mouth disease virus

Substantiating freedom from parasitic infection by combining transmission model predictions with disease surveys

Review of the Global Distribution of Foot-and-Mouth Disease Virus from 2007 to 2014

Contact Info

Product

Resources

About