Serological Diagnosis and Epidemiological impact of Helicobacter pylori infection on human health in Diyala Governorate, Iraq

Abstract

Helicobacter pylori (H. pylori) is one of the most common bacterial stomach infections and is implicated in a majority of stomach and duodenum ulcer as well as may be gastric cancer. The study showed that the incidence in diyala is nearly high comparing with the surrounding, little known about H. pylori prevalence in this population or other Native communities. In this cross-sectional study aimed to determine the prevalence of H. pylori among people subjects of different age groups ranged between 1 year to >50 years old. Two hundred and fifty of blood samples were collected from patients admitted Teaching hospitals in Baqubaa city and subjected to serological screening test.
 The results revealed that the prevalence of H. pylori antibody in human blood samples were 75.2%. the results appeared that H. pylori in males were more infected than females as the rate78.1% among males compared with females’ infection rate was 70%. The study also showed that the high prevalence rate of H. pylori antibody in the blood of patient’s age group 31-40 years was (77.8%), followed by the age group of 41-50 years (76.2%). Regarding risk factors, smoker males were the most infected with H. pylori (78.4%) compared to smoker females (31.7%). The results concluded that, the seroprevalence of H. pylori among human in Diyala Governorate was very high, and the infection occurred at all ages, particularly the youth ages

Review on Helicobacteriosis Associated Diseases

“…Subsequently, the Nobel Prize was conferred upon them in 2005 in recognition of their seminal contribution to the identification of H. pylori and its pivotal involvement in the pathogenesis of gastritis and peptic ulcer disease. [5][6].…”