Serological Evidence of Hantavirus in Humans and Rodents in Barbados

Groen, Jan; Koraka, Penelope; Edwards, Charles N.; Branch, Songee; Douglas, Kirk Osmond; Osterhaus, Albert D. M. E.; Levett, Paul N.

doi:10.1053/jinf.2002.1028

Cited by 14 publications

(16 citation statements)

References 12 publications

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“…The endemicity of the rodent born zoonosis Leptospirosis in this country also lends support to the findings from this study [20][21][22][23][24][25][26]. Interesting as early as 2002, Groen et al had reported serological evidence of hantavirus in humans and rodents in Barbados [27].…”

Section: Discussionsupporting

confidence: 84%

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Hantavirus infection among children hospitalized for febrile illness suspected to be dengue in Barbados

Kumar

Krishnamurthy

Nielsen

2016

Journal of Infection and Public Health

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Emerging picture of hantavirus infection in the South America is characterized by greater proportion of childhood infection and wider spectrum of disease from mild asymptomatic to lethal cardiopulmonary disease. Barbados is endemic for dengue and leptospirosis, both of which share clinical features with hantavirus infection and in many cases neither of these diagnosis could be confirmed. We investigate whether some of the children hospitalized with suspected dengue could indeed have been hantavirus infections. In this prospective study children hospitalized with suspected dengue were tested for hantavirus infection using ELISA for the IgM antibodies. Thirty-eight children tested positive for hantavirus infection. They presented with fever, headache and mild respiratory and gastrointestinal symptoms and signs. None of them had features suggestive of hantavirus cardiopulmonary syndrome. Blood count values ranged from low to normal to high for their age. There were no deaths. Hantavirus infection is prevalent in this Caribbean country. It predominantly presents with milder disease and is responsible for some of the nonspecific febrile illnesses in children.

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Section: Discussionsupporting

confidence: 84%

“…In the report from USA the age range for the infected children was from 10 to 16 years [33]. As noted earlier serological evidence of hantavirus transmission in this country was documented as early as the late nineties [27]. Infections noted at younger age in this study may reflect a changing epidemiology of hantavirus.…”

Section: Discussionsupporting

confidence: 59%

Hantavirus infection among children hospitalized for febrile illness suspected to be dengue in Barbados

Kumar

Krishnamurthy

Nielsen

2016

Journal of Infection and Public Health

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“…However, the Old World hantaviruses, especially the SEOV, have also been detected in the United States, Canada, and South American countries, although few clinical HFRS cases have been reported on the American continent [104,105]. Recently, Seoul-or Puumala-like hantavirus infections were reported in humans and rodents in the Caribbean country, Barbados [106].…”

Section: Americasmentioning

confidence: 99%

Hantavirus Infection: a review and global update

Formenty

Roth

2008

J Infect Dev Ctries

202

215

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Hantaviruses have the potential to cause two different types of diseases in human: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). HFRS, initially described clinically at the turn of the 20 th century, occurs endemically in the Asian and European continents, while HPS, recognized as a clinical entity since 1993, represents the prototype of emerging diseases occurring in the Western hemisphere. Approximately 150,000 to 200,000 cases of HFRS are hospitalized each year world wide, with most of the cases occurring in the developing countries. The case fatality rate of HFRS varies from <1% to 12% depending on the viruses. Although HPS is much smaller in number than HFRS, with approximately 200 HPS cases per year in the Americas, the average case fatality rate is 40%. The reported cases of hantaviral infection is increasing in many countries and new hantavirus strains have been increasingly identified worldwide, which constitutes a public health problem of increasing global concern. Hantaviral infection might be underestimated due to its asymptomatic and nonspecific mild infection, and the lack of simple standardized laboratory diagnostics in hospitals, especially in the developing countries. This review summarizes the current knowledge on virology, epidemiology, clinical manifestation, laboratory diagnostics, treatment and prevention of hantaviruses and hantaviral infections.

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“…This research found hantavirus IgM and IgG serological evidence in patients with suspected leptospirosis. Later serological evidence was also detected in Rattus norvegicus , an identified SEOV host, indicating that SEOV or other related hantaviruses might be present in Barbados [67]. In Trinidad and Tobago, a study evaluated the seroprevalence in healthy workers of livestock farms and slaughterhouse workers finding an 11.4% seroprevalence [68].…”

Section: Caribbean Islandsmentioning

confidence: 99%

Recent Evidence of Hantavirus Circulation in the American Tropic

Montoya-Ruiz

Díaz

Rodas

2014

Viruses

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Hantaan virus was discovered in Korea during the 1970s while other similar viruses were later reported in Asia and Europe. There was no information about hantavirus human infection in the Americas until 1993 when an outbreak was described in the United States. This event promoted new studies to find hantaviruses in the Americas. At first, many studies were conducted in Brazil, Argentina, Chile, Uruguay and Paraguay, while other Latin American countries began to report the presence of these agents towards the end of the 20th century. More than 30 hantaviruses have been reported in the Western Hemisphere with more frequent cases registered in the southern cone (Argentina, Chile, Uruguay, Paraguay, Bolivia and Brazil). However there was an important outbreak in 2000 in Panama and some rare events have been described in Peru, Venezuela and French Guiana. Since hantaviruses have only recently emerged as a potential threat in the tropical zones of the Americas, this review compiles recent hantavirus reports in Central America, the Caribbean islands and the northern region of South America. These studies have generated the discovery of new hantaviruses and could help to anticipate the presentation of possible future outbreaks in the region.

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Serological Evidence of Hantavirus in Humans and Rodents in Barbados

Cited by 14 publications

References 12 publications

Hantavirus infection among children hospitalized for febrile illness suspected to be dengue in Barbados

Hantavirus infection among children hospitalized for febrile illness suspected to be dengue in Barbados

Hantavirus Infection: a review and global update

Recent Evidence of Hantavirus Circulation in the American Tropic

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