Serological evidence of Rickettsia and Coxiella burnetii in humans of Buenos Aires, Argentina

Cicuttin, Gabriel L.; Degiuseppe, Juan Ignacio; Mamianetti, Andrea; Corin, Marcela Viviana; Linares, María Cielo; Salvo, María N. De; Dohmen, Federico E. Gury

doi:10.1016/j.cimid.2015.10.007

Cited by 15 publications

(10 citation statements)

References 24 publications

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“…The presence of novel MST and MLVA genotypes of C. burnetii in Brazil and Argentina raises the question of the importance of different lineages of C. burnetii in animal and human cases of Q fever, with a necessity of virulence studies to elucidate this question. The report of abortion in goats due to C. burnetii [22] and Q fever in humans in Brazil and Argentina [23][24][25][26] indicates the presence of virulent strains circulating in those countries. This is the first genotype study of Coxiella strains from Brazil and Argentina using MST and MLVA, molecular tools commonly used for this pathogen.…”

Section: Discussionmentioning

confidence: 99%

New Genotypes of Coxiella burnetii Circulating in Brazil and Argentina

et al. 2019

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Coxiella burnetii, the zoonotic agent of Q fever, has a worldwide distribution. Despite the vast information about the circulating genotypes in Europe and North America, there is a lack of data regarding C. burnetii strains in South America. Here, we show the presence of novel multispacer sequence typing (MST) genotypes of C. burnetii in two clusters detected in Brazil and Argentina that seem to be distant in parenthood. Argentinian strains isolated from a tick belongs to a new phylogenetic branch of C. burnetii, and the Brazilians strains may be related to MST 20 and 61. Multilocus variable number tandem repeats analysis (MLVA) typing provided a deeper resolution that may be related to host clusters of bovines, caprine, ovine, and ticks. Our results corroborate with the reports of geotypes of C. burnetii. Thus, we highlight the need for more genotyping studies to understand the genetic diversity of C. burnetii in South America and to confirm the hypothesis of host-related genotypes. We also emphasize the importance of virulence studies for a better understanding of Q fever in the region, which may help in surveillance and disease prevention programs.

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Section: Discussionmentioning

confidence: 99%

New Genotypes of Coxiella burnetii Circulating in Brazil and Argentina

et al. 2019

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“…In Argentina, exposure to this zoonotic agent was Cad. Saúde Pública 2018; 34(10):00193617 reported in people living under poor sanitary conditions with domestic animals, such as cats and dogs 49 . In countries like Spain, exposure to this microorganism has been detected in dairy cattle 50 and in sheep.…”

Section: Discussionmentioning

confidence: 99%

Serological evidence of exposure to some zoonotic microorganisms in cattle and humans with occupational exposure to livestock in Antioquia, Colombia

Eraso-Cadena

Molina-Guzmán

Cardona³

et al. 2018

Cad. Saúde Pública

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Bacteria belonging to Anaplasma, Ehrlichia, Rickettsia and Coxiella genera are considered emerging pathogens and livestock is one of the contexts where the transmission of these microorganisms can occur. The goal of this study was to determine serological evidence for the exposure to these bacteria in cattle and humans with occupational exposure to livestock in the subregions North and Magdalena Medio, Antioquia, Colombia, and to explore related factors. A cross-sectional study was conducted in 48 livestock farms distributed in six municipalities from both subregions: Belmira, Entrerríos and San Pedro de los Milagros (North), and Puerto Berrío, Puerto Nare and Puerto Triunfo (Magdalena Medio). Blood samples from 332 people and 384 bovines were evaluated by serology (IgM and IgG) screening for bacteria from the Anaplasma, Ehrlichia, Rickettsia, and Coxiella genera. Seropositivity in humans from both regions was 42.4% (95%CI: 31.2-55.1) for Anaplasma, 74.2% (95%CI: 66.0-84.4) for Ehrlichia, 72.5% (95%CI: 62.1-82.0) for Rickettsia, and 60.7% (95%CI: 59.7-69.1) for Coxiella burnetii. In cattle, seropositivity was 31.6% (95%CI: 19.9-44.2), 66.8% (95%CI: 55.2-78.1), 64.6% (95%CI: 53.8-74.5), and 61.6% (95%CI: 51.9-69.2), respectively. History of biting by ticks, milking, vaccination, having dogs and hens in the residence, as well as the consumption of raw milk derivatives were some factors associated with the infection by the bacteria studied. The results suggest a previous and recent exposure to these zoonotic bacteria genera in people with occupational exposure to livestock, as well as in cattle in the two studied subregions.

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“…41 Clinicians evaluating returned travelers frequently entertain rare or exotic diagnoses. Travel-related cases of pulmonary infections due to Mycobacterium tuberculosis, 41 influenza, measles, Coccidioides immitis, 42 Paracoccidioides brasiliensis, 43 Histoplasma capsulatum, 43 Burkholderia pseudomallei, 44 hantavirus, 45,46 L. pneumophila, 47,48 and Coxiella burnetii 49 have been described. Emergent coronaviruses have been described during the last years in travelers returning from abroad, including the severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS).…”

Section: Region-specific Pathogensmentioning

confidence: 99%

Community-Acquired Pneumonia in Latin America

Iannella

Luna

2016

Semin Respir Crit Care Med

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Community-acquired pneumonia (CAP) is associated with significant morbidity and mortality in Latin America and the Caribbean (LAC) region. Poverty, socioeconomic factors, and malnutrition influence the incidence and outcome of CAP in LAC. In LAC, is the most frequent microorganism responsible for CAP, (incidence: 24-78%); the incidence of atypical microorganisms is similar to other regions of the world. Human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) is a growing problem in the LAC region, with the Caribbean being the second most affected area worldwide after Sub-Saharan Africa. Pneumococcal pneumonia remains the most common cause of CAP in HIV-infected patients, but and tuberculosis (TB) are also common in this population. The heterogeneity of the health care systems and social inequity between different countries in LAC, and even between different settings inside the same country, is a difficult issue. TB, including multidrug-resistant TB, is several times more common in South American and Central American countries compared with North America. Furthermore, hantaviruses circulating in the Americas (new world hantaviruses) generate a severe respiratory disease called hantavirus pulmonary syndrome, with an associated mortality as high as 50%. More than 30 hantaviruses have been reported in the Western Hemisphere, with more frequent cases registered in the southern cone (Argentina, Chile, Uruguay, Paraguay, Bolivia, and Brazil). Respiratory viruses (particularly influenza) remain an important cause of morbidity and mortality, particularly in the elderly. Low rates of vaccination (against influenza as well as pneumococcus) may heighten the risk of these infections in low- and middle-income countries.

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Serological evidence of Rickettsia and Coxiella burnetii in humans of Buenos Aires, Argentina

Cited by 15 publications

References 24 publications

New Genotypes of Coxiella burnetii Circulating in Brazil and Argentina

New Genotypes of Coxiella burnetii Circulating in Brazil and Argentina

Serological evidence of exposure to some zoonotic microorganisms in cattle and humans with occupational exposure to livestock in Antioquia, Colombia

Community-Acquired Pneumonia in Latin America

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