Serological study of toxoplasmosis in pregnant women in Jahrom city, 2018

Maani, Salar; Kazemi, Mohammad; Solhjoo, Kavos; Shadmand, Enayatollah; Rezanezhad, Hassan

doi:10.52547/jmj.18.2.1

Cited by 4 publications

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“…In the other hand, the anti T. gondii IgM antibodies prevalence of up to 4% was reported in some studies ( 19 , 21 , 22 , 26 , 30 , 32 ), but other researchers observed lower than 4% ( 10 , 16 , 18 , 23 , 25 ). In other studies none of participants had anti T. gondii IgM antibodies ( 20 , 24 , 27 , and 28 ), that is in accordance with the results of current study.…”

Section: Discussionsupporting

confidence: 93%

Seroprevalence of Toxoplasma gondii among Pregnant Women in Ardabil, Iran (2021-2022)

Hariri¹,

Heidari²,

Habibzadeh³

et al. 2023

IJPA

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Background: Toxoplasmosis during pregnancy can causes adverse outcomes. Regarding its importance in prenatal care, seroprevalence of Toxoplasma gondii infection among pregnant women was studied in Ardabil City, during 2021-2022. Methods: In a cross–sectional study with a cluster sampling, 244 pregnant women that attended in health care centers of Ardabil City, Ardabil Province, Iran in 2021-2022 were selected. Serum samples were collected and Anti- Toxoplasma IgM (immunoglobulin M) and IgG (immunoglobulin G) was detected. Furthermore, a questionnaire filled for all participants during samples collection and risk factors assessed. Data were analyzed by SPSS software. Results: Participant's age ranged from 16 to 43 years with average of 23± 5.24 years. IgG anti- T. gondii antibody was detected in 22.1% of pregnant women (54/244). In none of participants IgM anti- Toxoplasmosis antibody was detected. There was no significant relationship between demographic variables and risk factors of toxoplasmosis with serology test results. Conclusion: Approximately, 77.9% of pregnant women had no antibody against the T. gondii infection. Therefore, health education, counseling of pregnant women and screening in high-risk pregnant women is recommended to prevent from fetal complications.

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Section: Discussionsupporting

confidence: 93%

Seroprevalence of Toxoplasma gondii among Pregnant Women in Ardabil, Iran (2021-2022)

Hariri¹,

Heidari²,

Habibzadeh³

et al. 2023

IJPA

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“…The study indicated that anti- T. gondii IgG was positive among 17.5% and 14% of the case and control groups, respectively [ 26 ]. Although the seroprevalence rates of T. gondii in these two studies [ 25 , 26 ] were lower than in the current study, the comparison of our results with them could not be accurate because the age ranges of our study were between 34 and 80 years old, but the age ranges in these two studies [ 25 , 26 ] were under 40 years old. It should be noted that the seroprevalence rate of toxoplasmosis could increase with increasing age [ 27 ].…”

Section: Discussioncontrasting

confidence: 86%

“…It should be noted that the seroprevalence rate of toxoplasmosis could increase with increasing age [ 27 ]. Other studies in Fars Province revealed a seroprevalence rate ranging between 7.5% and 29% [ 25 , 28 – 31 ] ( Table 2 ).…”

Section: Discussionmentioning

confidence: 91%

“…Previous studies in the same region (Jahrom County) revealed that the prevalence rates of toxoplasmosis were lower than in our study. In this regard, Maani et al [ 25 ] assessed the seroprevalence rates of toxoplasmosis among 370 pregnant women in Jahrom City, and accordingly, anti- T. gondii IgG and IgM were detected in 29.5% and 0.5% of pregnant women, respectively. Another study in the same region was conducted among 120 pregnant women with a history of recurrent abortion (case group) and 50 women with normal delivery (control group) [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

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Latent Toxoplasmosis among Breast Cancer Patients in Jahrom, South of Iran

Haghbin

Maani

Bagherzadeh

et al. 2023

International Journal of Breast Cancer

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Objective. Reactivation of latent toxoplasmosis is the main cause of severe infection among immunocompromised patients, including patients with cancer. Hence, this study is aimed at screening the status of Toxoplasma gondii infection among breast cancer patients by serological and molecular methods and determining their associated risk factors in Jahrom County, Fars Province, south of Iran. Methods. One hundred and seven women with breast cancer (aged 34 to 80 years) were screened for anti-T. gondii antibodies (IgG and IgM) during 2019–2020. A questionnaire regarding demographic factors was filled out by participants. Molecular detection was performed by polymerase chain reaction (PCR) using the primer pair targeting the repetitive element (RE) gene of T. gondii. The risk factors and demographic data were analyzed by SPSS software (ver. 20, Chicago, IL, USA) using the Chi-squared test. Results. Anti-T. gondii IgG was detected in 45.8% (49/107) of the patients, which indicates latent infection, but anti-T. gondii IgM and PCR were negative in all samples. Demographic factors revealed a statistically significant increased T. gondii seropositivity among nonmenopause cancer patients ( P < 0.0005 ), patients without previous breast cancer ( P = 0.0001 ), and human epidermal growth factor receptor 2- (HER2-) negative patients ( P = 0.00002 ). As such, patients with a history of previous abortions and who were at stages II, III, and IIII of cancer had higher seropositivity rates than patients without a history of previous abortions or who were at stage I cancer, but the statistical analysis was not significant. We did not find a statistically significant association between T. gondii seropositivity and other risk factors of toxoplasmosis (e.g., education level, type of water source, washing raw fruits and vegetables, consumption of raw or undercooked meat, and contact with soil, cats, and domestic animal). Conclusion. A high seroprevalence rate of latent T. gondii infection was detected among patients with breast cancer; hence, these patients may be at high risk for reactivation of latent infection. Screening of T. gondii infection is recommended to detect active infection among patients with malignancies.

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“…In this study, out of 240 married women, 62 participants (25.8%) had anti- Toxoplasma antibody titers, which was less than Dalimi et al ( 14 ) research results in pregnant women (26.3%), Hazrat-e-Tappeh et al ( 15 ) (28.3%), Naeini et al ( 16 ) (37.3%), Hosseini et al ( 17 ) (58.8%), Kalantari et al ( 18 ) (60.6%) and Abdi.et al ( 19 ) (44.8%). However, it was higher than studies conducted by Jones et al ( 20 ) and the prevalence rates reported by toxoplasmosis (0.88), Norouz Larki et al ( 21 ) (8.9) or Wei Cong et al ( 22 )(15.2) in pregnant women ( 20 – 22 ).…”

Section: Discussioncontrasting

confidence: 59%

Comparison of Toxoplasmosis Seroprevalence in Multi Partner, Married (Monogamous) and Virgin Iranian Women

Shajarizadeh,

Biderouni,

Sohrabi

et al. 2023

IJPA

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Background: Toxoplasmosis could lead to serious outcomes during pregnancy. The aim of this study was to investigate serologic toxoplasmosis in three groups of women according to number of sexual partners. Methods: The frequency of anti-Toxoplasma IgG from 471 women (101 virgin girls, 240 married women and 130 multi partner women) were determined by ELISA method from referred participant to medical centers of Tehran, Iran in 2020. The results were analyzed by chi-square and logistic regression tests. Results: Prevalence of toxoplasmosis was significant with the number of sexual partner according to chi square test (P<0.001) and the highest one was observed in multi partners’ women (56.2%) and the lowest one in virgin girls (17.8%). ORs of virgin girls and multi partners’ women were 0.594 and 3.758 respectively, compared to married women. The effect of age on the frequency of anti-Toxoplasma IgG in married women was significant but it was not significant in multi partners’ women. In addition to IgG frequency in married women and multi partners’ women had no significant relationship with the number of children. Conclusion: Having sexual activity after marriage and having multi partner in sexual activity may possibly be a novel risk factor for toxoplasmosis infection or increasing the IgG frequency.

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Serological study of toxoplasmosis in pregnant women in Jahrom city, 2018

Cited by 4 publications

References 0 publications

Seroprevalence of Toxoplasma gondii among Pregnant Women in Ardabil, Iran (2021-2022)

Seroprevalence of Toxoplasma gondii among Pregnant Women in Ardabil, Iran (2021-2022)

Latent Toxoplasmosis among Breast Cancer Patients in Jahrom, South of Iran

Comparison of Toxoplasmosis Seroprevalence in Multi Partner, Married (Monogamous) and Virgin Iranian Women

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