Seropositivity of <i>Bartonella henselae</i> in Risky Human Population, Cats and Dogs

Abstract

Amaç: Bartonella türleri insanlarda kedi tırmığı hastalığı, basiller anjiomatozis, basiller peliozis, Carrion hastalığı, enfektif endokardit ve siper ateşi gibi pek çok hastalığa yol açmaktadır. Türkiye'de Bartonella'lara bağlı kedi tırmığı hastalığı ve basiller anjiomatozis olgu sunuları bulunmaktadır. Bu çalışmada, Türkiye'nin batısında, kedi/kopek sahibi riskli insan, kedi ve köpeklerdeki Bartonella henselae seropozitivitesinin araştırılması amaçlanmıştır. Gereç ve Yöntemler: Bu çalışmaya, 34'ü ev, 97'si sokak olmak üzere toplam 131 kedi/köpek sahibi ve 57'si ev kedisi, 48'i barınak kedisi olmak üzere toplam 105 kedi ile 45 ev köpeğinin serum örnekleri alınmıştır. Serum örneklerinde B. henselae IgG antikorları iki ticari kit kullanılarak immunfluoresan antikor yöntemi ile belirlenmiştir. Bulgular: B. henselae seropozitifliği, ev kedi/köpek sahiplerinde sokak kedi/köpek sahiplerine göre (sırasıyla %26,5 ve %6,8). Seropozitiflik, istatistiksel olarak anlamlı Objective: Bartonella species cause several diseases in humans such as cat scratch disease, bacillary angiomatosis, peliosis hepatis, endocarditis, Carrion disease and trench fever. There have been cat scratch disease and bacillary angiomatosis cases reports in Turkey. The aim of this study is to determine the seropositivity against Bartonella henselae in cat/dog owners who are in the risk group, cats and dogs in Western Aegean region, Turkey. MaterialsandMethods:In this study, B. henselae immunoglobulin (Ig) G positivity was investigated in a total of 281 samples including a total of 131 people, 34 of whom are pet cat/dog owners and 97 of whom are stray cat/dog owners; as well as a total of 105 cats, of which 57 pet cats, 48 shelter cats, and 45 pet dogs. Sera tested for the presence of antibodies against B. henselae IgG using immunofluorescence assay with two commercial kits. Results: B. henselae seropositivity of pet owners was significantly higher than the stray cat/dog owners (26.5% vs 6.8%). B. henselae IgG was found positive in 36.2% of total cats, 22.8% of pet cats, 52.1% of shelter cats. B. henselae seropositivity was found statistically higher in shelter cats than pet cats. No positivity was detected in the samples taken from the dogs. Conclusion: It is concluded that being pet owner at home poses a risk for B. henselae. For the differential diagnosis, especially in patients in close contact with cats, B. henselae infection should be considered.

A Man in His Forties with Recurrent Cat-Scratch Disease

“…The risk of transmission between humans and cats has not been determined. However, a study conducted in Turkey found an 11.5% seroprevalence in a simultaneously assessed sample in cat/dog [ 5 ]. Additionally, in Chile, 18.1% of owners with positive cats (71.0%) exhibited antibodies against B. henselae [ 6 ].…”

Protozoan and Microbial Pathogens of House Cats in the Province of Tekirdag in Western Turkey

“…Earlier in the country, PCR tests confirmed the presence of B. henselae in cats of Ankara (8.2% to 18.6%) [ 56 ], Istanbul (28.1%) [ 57 ], and Izmir (8%) [ 58 ], while B. henselae seropositivity was 34.4% of 186 cats examined in Konya [ 59 ], 41.3% in Bursa, 33.9% in Adana, and 27.5% in Aydin [ 60 ]. In the Western Aegean region of the country, B. henselae IgG seropositivity was higher in pet cat and pet dog owners than in those who were caring for stray cats and stray dogs in their neighborhood (26.5% and 6.8%, respectively) [ 61 ]. In addition, the seroprevalence in veterinarians and cattle herders was 30% and 12.5%, respectively, in the Aydin and Denizli Provinces [ 62 ].…”

Akut lenfadenit ile gelen bir kedi tırmığı olgusu

“…Bölgemizde kedilerde yapılan bir çalışmada Bartonella taşıyıcılığı %12 olarak bildirilmiştir [6]. B.henselae IgG seropozitifliği evcil hayvan (kedi/köpek) sahiplerinde %26,5 oranında bulunmuştur [7]. Büyük hastalık veri tabanlarında yapılan analizlerde hastalığın yarısından fazlasının 18 yaş altındaki kişilerde görüldüğü bildirilmiştir [8].…”