Seropositivity rates for toxoplasmosis, rubella, syphilis, cytomegalovirus, hepatitis and HIV among pregnant women receiving care at a Public Health Service, São Paulo State, Brazil

Abstract

Infectious and parasitic diseases affecting women during their reproductive age may result in vertical transmission. The aim of this study was to determine the seroprevalence for TORSCH among pregnant women receiving care at a university hospital. Records of 574 pregnant women who received medical attention from January 2006 to December 2007 were assessed. The mean age was 27.2 ± 6.5 years ranging from 13 to 44. The results of the immunodiagnostic tests were: 62.0% (345/556) for IgG and 3.4% (19/556) for IgM anti-T. gondii; 93.1% (433/465) for IgG and 0.6% (3/465) for IgM anti-rubella; 0.9% (5/561) for VDRL; 1.8% (10/554) for HBsAg; 0.7% (4/545) for anti-HCV and 2.1% (11/531) for HIV. In conclusion, the results of immunodiagnostic tests for the TORSCH panel among pregnant women attending a perinatal service of a university hospital are in agreement with those reported by previous studies and by governmental sources.

Anti-Toxoplasma gondii antibodies in pregnant women and their newborn infants in the region of São José do Rio Preto, São Paulo, Brazil

“…Our results showed that 64.4% of the women with high-risk pregnancies had toxoplasmosis. These data suggest that the rate of positive findings of T. gondii infection was high in this group and thus corroborate other studies from the same region of the state of São Paulo 20,23 and from other Brazilian states. [15][16][17][24][25][26][27][28] The similarities between this and other studies carried out in some Brazilian states [15][16][17]28 may reflect homogeneity regarding the laboratory diagnostic strategies used.…”

Rubella seroprevalence in pregnant women at the military teaching hospital, Rabat, Morocco

“…Indeed, the data collected before 2003 among women of childbearing age showed 66.5%–85.5% seropositivity for anti‐rubella virus IgG. Rubella seroprevalence reported in previous international studies ranged between 85.5% and 93% [1,3]. Comparison of seroprevalence levels between studies is difficult owing to the different designs, sampling, timing of studies in relation to previous outbreaks, variability of laboratory procedures, and titer cut‐off points used to define positivity of anti‐rubella IgG.…”

Human extracellular vesicles and correlation with two clinical forms of toxoplasmosis

“…Clinical diagnosis of cerebral toxoplasmosis in HIV-infected patients was based on: 1) progressive neurological deficits; 2) contrast-enhancing mass lesion(s) on computed tomography and/or magnetic resonance imaging; and 3) successful clinical and radiological response to antiparasitic treatment within 10-14 days [13,14]. Pregnant women with suspicion of acute toxoplasmosis infection were admitted and treated at the High-Risk Antenatal Care and Fetal Medicine Service (Hospital de Base, Sao José do Rio Preto, Brazil) After enrolling in a high-risk pregnancy clinic, pregnant women were routinely screened for TORSCH (Toxoplasmosis, Rubella, Syphilis, Cytomegalovirus, Hepatitis and HIV) [37,38] Those clinically, epidemiologically suspected of toxoplasmosis and having positive IgM or low IgG avidity for anti-T. gondii antibodies were underwent to amniocentesis and peripheral blood for PCR. Before collection pregnant women were informed of the procedure and signing informed-consent forms.…”