Seropositivity rates for toxoplasmosis, rubella, syphilis, cytomegalovirus, hepatitis and HIV among pregnant women receiving care at a public health service, São Paulo state, Brazil

Abstract

Infectious and parasitic diseases affecting women during their reproductive age may result in vertical transmission. The aim of this study was to determine the seroprevalence for TORSCH among pregnant women receiving care at a university hospital. Records of 574 pregnant women who received medical attention from January 2006 to December 2007 were assessed. The mean age was 27.2 ± 6.5 years ranging from 13 to 44. The results of the immunodiagnostic tests were: 62.0% (345/556) for IgG and 3.4% (19/556) for IgM anti-T. gondii; 93.1% (433/465) for IgG and 0.6% (3/465) for IgM anti-rubella; 0.9% (5/561) for VDRL; 1.8% (10/554) for HBsAg; 0.7% (4/545) for anti-HCV and 2.1% (11/531) for HIV. In conclusion, the results of immunodiagnostic tests for the TORSCH panel among pregnant women attending a perinatal service of a university hospital are in agreement with those reported by previous studies and by governmental sources

Toxoplasmose ocular com reação em cadeia da polimerase positiva em sangue periférico – relato de dois casos, estado de São Paulo, Brasil

“…A previous report shows that around 27% of patients treated at an ophthalmology outpatient clinic had clinical evidence of OT [15]. Contact with soil and pets was regarded as an important risk factor for T. gondii infection, which also affects about 65% of pregnant women in this region [16][17][18]. These data are consistent with reports from other Brazilian regions [5,[19][20][21].…”

Prevalence of infections with potential for vertical transmission in pregnant women seen ata University Hospital in southern Brazil

“…16 No entanto esta prevalência encontra-se dentro dos valores de 1 a 4,4% de gestantes portadoras de Sífilis estimados pela Organização Mundial da Saú-de para o Brasil. 17 Os estudos realizados em gestante no Brasil apresentam uma prevalência de Sí-filis variada entre 0,8% e 4,4%, 14,15,18 sendo as maiores taxas encontradas no Sul do Brasil.…”

“…Ressaltamos que as prevalên-cias de toxoplasmose encontradas nas gestantes desse estudo encontram-se entre as taxas referidas por outros trabalhos nacional onde a prevalên-cia de IgG vária entre 54 e 91% e de IgM entre 0,4 a 3,4%. 3,14,15,18,20,21 Esses valores mostram a importância da triagem pré-natal para esta infecção e das orientações profiláticas as gestantes sem imunidade prévia, pois a literatura confirma a existên-cia de infecção aguda neste período.…”

“…A taxa de hepatite B encontrada nesse estudo foi inferior ao encontrada em outros estudos realizados com gestante nos pais, onde essa vária de 0,3 a 1,8%. 3,14,18,22 Como o rastreio da hepatite C não é obrigatória no protocolo de pré-natal do MS 8 são raros os estudos com esta infecção. No entanto, pesquisa realizada com 2037 gestantes atendidas nas unidades de saúde de Goiás observou uma prevalência de hepatite C de 0,3%.…”

Clinical and epidemiological profile of female blood donors with positive serology for viral hepatitis B

“…The prevalence of the disease is known to infl uence the specifi city of diagnostic tests: in low-prevalence settings, even very good tests have poor positive predictive value (31) . HBsAg prevalence in Brazil is low, with reports ranging from 0.6% to 0.8% (18) (32) . The designation of borderline cases as positive would cause false-positive tests to avoid false-negative results, which may be more harmful than false positives (33) .…”