Seroprevalence and detection of Rickettsia spp. in wild birds of Arauca, Orinoquia region, Colombia

Cardona‐Romero, Marelid; Martínez‐Sánchez, Estefani T.; Alvarez-Londoño, Johnathan; Pérez-Cárdenas, Jorge E.; Ossa‐López, Paula A.; Castaño‐Villa, Gabriel J.; Binder, Lina C.; Faccini-Martínez, Álvaro A.; Rivera‐Páez, Fredy A.

doi:10.1016/j.vprsr.2022.100720

Cited by 6 publications

(5 citation statements)

References 50 publications

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“…This list includes a wide variety of animals, with the most common including humans, wild birds, dogs, horses, deer, and others ( Table 1 ). Birds in particular play an important role in tick-borne diseases by spreading pathogenic bacteria over long distances to new areas [ 122 , 147 , 192 , 193 ]. Studies on infected ticks feeding on birds have the potential to explain some of the distribution patterns of R. amblyommatis .…”

Section: Distribution and Spread Of Rickettsia Amblyommatismentioning

confidence: 99%

Rickettsia amblyommatis in Ticks: A Review of Distribution, Pathogenicity, and Diversity

et al. 2023

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Rickettsia amblyommatis is a potentially pathogenic species of Rickettsia within the spotted fever group vectored by ticks. While many studies have been published on this species, there is debate over its pathogenicity and the inhibitory role it plays in diagnosing illnesses caused by other spotted fever group Rickettsia species. Many publications have recorded the high infection prevalence of R. amblyommatis in tick populations at a global scale. While this species is rather ubiquitous, questions remain over the epidemiological importance of this possible human pathogen. With tick-borne diseases on the rise, understanding the exact role that R. amblyommatis plays as a pathogen and inhibitor of infection relative to other tick-borne pathogens will help public health efforts. The goal of this review was to compile the known literature on R. amblyommatis, review what we know about its geographic distribution, tick vectors, and pathogenicity, assess relatedness between various international strains from ticks by phylogenetic analysis and draw conclusions regarding future research needed.

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Section: Distribution and Spread Of Rickettsia Amblyommatismentioning

confidence: 99%

Rickettsia amblyommatis in Ticks: A Review of Distribution, Pathogenicity, and Diversity

et al. 2023

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“…In addition to molecular detection, in Colombia there is evidence of R. amblyommatis exposure in humans and animals, evidenced by the detection of antibodies against this species or against antigenically close species using indirect immunofluorescence assay (IFA) in human and animal samples from the departments of Antioquia and Arauca [ 39 , 40 ]. This exposure is important mainly because of the role that these bacteria seem to play in rickettsiosis cycles.…”

Section: Discussionmentioning

confidence: 99%

First isolation of Rickettsia amblyommatis from Amblyomma mixtum in Colombia

Chaparro-Gutiérrez,

Acevedo-Gutiérrez,

Mendell

et al. 2023

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Background Rickettsiae are obligate intracellular Gram-negative bacteria that are the causative agent of rickettsioses and are spread to vertebrate hosts by arthropods. There are no previous reports of isolation of Rickettsia amblyommatis for Colombia. Methods A convenience sampling was executed in three departments in Colombia for direct collection of adult ticks on domestic animals or over vegetation. Ticks were screened for the presence of Rickettsia spp. by real-time polymerase chain reaction (qPCR) amplifying the citrate synthase gene (gltA), and the positive sample was processed for isolation and further molecular characterization by conventional PCR. The absolute and relative frequencies were calculated for several tick species variables. All products from conventional PCR were further purified and sequenced by the Sanger technique. Representative sequences of 18 Rickettsia species were downloaded from GenBank. Consensus phylogenetic trees were constructed for the gltA, ompB, ompA, and htrA genes with 1000 replicates, calculating bootstrap values through the maximum likelihood method and the generalized time reversible substitution model in the MEGA 7.0 software program. Results One female Amblyomma mixtum collected on vegetation was amplified by qPCR (gltA), indicating a frequency of 1.6% (1/61) for Rickettsia spp. infection. Sequence analysis of a rickettsial isolate from this tick in BLASTn showed 100% identity with gltA (340 base pairs [bp]), 99.87% for ompB (782 bp), 98.99% for htrA (497 bp), and 100% for ompA (488 bp) to R. amblyommatis. Concatenated phylogenetic analysis confirmed these findings indicating that the isolate is grouped with other sequences of Amblyomma cajennense complex from Panama and Brazil within the R. amblyommatis clade. Conclusions This paper describes the isolation and early molecular identification of a R. amblyommatis strain from A. mixtum in Colombia. Graphical Abstract

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“…Considering the animal host diversity around outbreak regions, studies have also implicated several sylvatic hosts as possible SFGR reservoirs. Birds have been studied, given their migration patterns and travel distances, and could be considered important reservoir hosts [ 31 , 77 , 79 , 80 ]. Although limited evidence exists on SFG rickettsiosis prevalence among birds, knowledge on tick infestation rates and species associated with birds may yield some information on possible enzootic cycles [ 80 ].…”

Section: Serological Evidencementioning

confidence: 99%

Spotted Fever Group Rickettsia spp. Molecular and Serological Evidence among Colombian Vectors and Animal Hosts: A Historical Review

Gual-Gonzalez,

Torres,

Self

et al. 2024

Insects

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Spotted fever group Rickettsia spp. (SFGR) are a large group of tick-borne bacteria causing important emerging and re-emerging diseases that affect animals and humans. While SFGR are found worldwide, a lack of surveillance and misdiagnosis particularly affect South American countries. Colombia is a high burdened country in South America, yet rickettsioses are not deemed a nationally reportable condition limiting disease-specific public health resources. As mortality rates are high for one Rickettsia pathogen species, there is a great need to better understand the epidemiological and ecological factors that increase SFGR transmission risk regionally. This literature review provides an overview of Colombia-based SFGR studies connecting knowledge about both vectors and hosts.

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Seroprevalence and detection of Rickettsia spp. in wild birds of Arauca, Orinoquia region, Colombia

Cited by 6 publications

References 50 publications

Rickettsia amblyommatis in Ticks: A Review of Distribution, Pathogenicity, and Diversity

Rickettsia amblyommatis in Ticks: A Review of Distribution, Pathogenicity, and Diversity

First isolation of Rickettsia amblyommatis from Amblyomma mixtum in Colombia

Spotted Fever Group Rickettsia spp. Molecular and Serological Evidence among Colombian Vectors and Animal Hosts: A Historical Review

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