Seroprevalence and risk factors of brucellosis in abattoir workers at Debre Zeit and Modjo export abattoir, Central Ethiopia

Tsegay, Amanuel; Tuli, Getachew; Kassa, Tesfu; Kebede, Nigatu

doi:10.1186/s12879-017-2208-0

Cited by 28 publications

(27 citation statements)

References 15 publications

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“…A total of 292 individuals working in slaughterhouses were described as brucellosis-positive in fourteen articles [19,20,23,33,34,[41][42][43][44][45][46][47][48][49]. Most of those individuals were from America (n = 162), Africa (n = 60), and Europe (n = 37) and the minority from Asia (n = 33).…”

Section: Abattoir Workersmentioning

confidence: 99%

“…The main type of pathogen exposure reported was contact with animal fluids, aborted fetus, placenta and viscera. Accidental contact with those materials was described in three studies: in Spain and Ethiopia, 12.26% (13/106) and 48.72% (76/156) of slaughterhouse workers, respectively, reported cutting themselves with dirty sharp blades [45,46], and in China, 100.00% (3/3) of pharmaceutical employees, who worked processing sheep placenta, reported having splashed animal fluids on their faces [47]. The great occurrence of direct contact with biological contaminated fluids aroused the interest of several authors to understand which PPE were used or not by this group of professionals (Table 2).…”

Section: Abattoir Workersmentioning

confidence: 99%

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Occupational exposure to Brucella spp.: A systematic review and meta-analysis

et al. 2020

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Brucellosis is a neglected zoonotic disease of remarkable importance worldwide. The focus of this systematic review was to investigate occupational brucellosis and to identify the main infection risks for each group exposed to the pathogen. Seven databases were used to identify papers related to occupational brucellosis: CABI, Cochrane, Pubmed, Scielo, Science Direct, Scopus and Web of Science. The search resulted in 6123 studies, of which 63 were selected using the quality assessment tools guided from National Institutes of Health (NIH) and Case Report Guidelines (CARE). Five different job-related groups were considered greatly exposed to the disease: rural workers, abattoir workers, veterinarians and veterinary assistants, laboratory workers and hunters. The main risk factors and exposure sources involved in the occupational infection observed from the analysis of the articles were direct contact with animal fluids, failure to comply with the use of personal protective equipment, accidental exposure to live attenuated anti-brucellosis vaccines and non-compliance with biosafety standards. Brucella species frequently isolated from job-related infection were Brucella melitensis, Brucella abortus, Brucella suis and Brucella canis. In addition, a metaanalysis was performed using the case-control studies and demonstrated that animal breeders, laboratory workers and abattoir workers have 3.47 [95% confidence interval (CI); 1.47-8.19] times more chance to become infected with Brucella spp. than others individuals that have no contact with the possible sources of infection. This systematic review improved the understanding of the epidemiology of brucellosis as an occupational disease. Rural workers, abattoir workers, veterinarians, laboratory workers and hunters were the groups more exposed to occupational Brucella spp. infection. Moreover, it was observed that the lack of knowledge about brucellosis among frequently exposed professionals, in addition to some behaviors, such as negligence in the use of individual and collective protective measures, increases the probability of infection.

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Section: Abattoir Workersmentioning

confidence: 99%

Section: Abattoir Workersmentioning

confidence: 99%

Occupational exposure to Brucella spp.: A systematic review and meta-analysis

et al. 2020

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“…The human seropositive case reported in this study was from the group of cleaners. Swai and Schoonman (2009) and Tsegay et al (2017) argued that cleaners in the abattoir being the least educated group may lack knowledge on how brucellosis is transmitted. On the other hand, since they are most heavily involved in handling and disposing all condemned abattoir materials including aborted foetuses that usually have very high concentrations of Brucella pathogens; they are at a much higher risk of infection when compared to other groups.…”

Section: Discussionmentioning

confidence: 99%

Occupational hazards associated with human brucellosis in abattoir settings: A case study of Dodoma abattoir in Tanzania

Luwumba¹,

Kusiluka²,

Shirima³

2019

J. Vet. Med. Anim. Health

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Brucellosis is one of the most widespread zoonotic diseases posing a serious obstacle to public health, food safety and security and, socioeconomic development in most African countries. A cross-sectional study was conducted to establish practices that may pose occupational risks of transmission of brucellosis to people working in abattoirs in Tanzania. A total of 452 serum samples; 190, 200 and 62 from cattle, goats and human, respectively were collected in animals and workers at Dodoma abattoir, Tanzania. The samples were screened for brucellosis using Rose Bengal Plate test (RBPT) and indirect enzyme-linked immunosorbent assay (iELISA). A semi-structured questionnaire was used to collect data for assessing the knowledge, awareness and practices related to brucellosis exposure. Data were analyzed to determine the association of brucellosis seropositivity with the knowledge, awareness and practices of the workers. The seroprevalence of brucellosis in cattle, goats and abattoir workers was 7.3, 1.5 and 1.6%, respectively based on Rose Bengal Plate Test. The seroprevalence was 4.7% in cattle, 1.6% in humans and none in goats when samples were tested by indirect enzyme-linked immunosorbent assay. The results of this study show that, there is a potential occupational risk of acquisition of brucellosis for abattoir workers and hence, the need for awareness campaigns and taking appropriate precautions to minimize the zoonotic risks is greatly required.

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“…Serologic studies performed in other countries presented differing proportions of human brucellosis seroprevalences among slaughterhouse workers. For instance, a Nigerian study found that the brucellosis seroprevalence was 59.3% among butchers [ 27 ], while an Ethiopian study found that the seroprevalence in abattoir workers, as determined by the Rose Bengal plate test, was 4.7% [ 28 ]. Additionally, the brucellosis seroprevalence was reported to be 10.3% (using SAT) in Uganda and 7.9% (using ELISA) in Iran [ 11 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

Seroreactivity and Risk Factors Associated with Human Brucellosis among Cattle Slaughterhouse Workers in South Korea

Acharya

Hwang

Park

2018

IJERPH

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The prevalence rate of human brucellosis in high-risk populations, as well as their risk factors, have not been well understood in South Korea. In this cross-sectional study, we investigated the seroreactivity and risk factors associated with human brucellosis among South Korean cattle slaughterhouse workers. We enrolled 922 subjects working in 71 slaughterhouses across the country in 2012. A structured questionnaire was used to obtain data from the subjects, following which blood samples were collected and tested using the microagglutination test; serum titers ≥ 1:20 were considered reactive. Independent risk factors were identified using multivariate logistic regression analysis with backward elimination. Overall, 62 of 922 participants (6.7%) exhibited seroreactivity for brucellosis, and 0.4% had a seroprevalence at a dilution of 1:160. Multivariate analysis revealed that the risk factors for human brucellosis seroreactivity included large-scale slaughtering (≥100 cattle per day; odds ratio (OR), 5.41; 95% confidence interval (CI), 2.95–9.91) and medium-scale slaughtering (50–99 cattle per day; OR, 2.53; 95% CI, 1.16–5.51). Moreover, the risk of brucellosis infection was significantly lower among slaughterhouse workers who always wear protective glasses (OR, 0.27; 95% CI, 0.11–0.69) than in those who sometimes or rarely wore such glasses. Regular and consistent use of personal protective equipment, especially protective glasses, should be encouraged among cattle slaughterhouse workers to reduce brucellosis infection.

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Seroprevalence and risk factors of brucellosis in abattoir workers at Debre Zeit and Modjo export abattoir, Central Ethiopia

Cited by 28 publications

References 15 publications

Occupational exposure to Brucella spp.: A systematic review and meta-analysis

Occupational exposure to Brucella spp.: A systematic review and meta-analysis

Occupational hazards associated with human brucellosis in abattoir settings: A case study of Dodoma abattoir in Tanzania

Seroreactivity and Risk Factors Associated with Human Brucellosis among Cattle Slaughterhouse Workers in South Korea

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