Seroprevalence and risk factors of tick-borne encephalitis in Mongolia between 2016 and 2022

Ganbold, Dashdavaa; Uudus, Bayarsaikhan; Nyamdavaa, Naranbat; Chultemsuren, Yeruult; Zagd, Amarbayasgalan; Tangad, Mungunzaya; Badrakh, Burmaa; Baldandorj, Bolorchimeg; Dogsom, Ochgerel; Lkunrev, Rolomjav; Baasandagva, Uyanga; Nyamdorj, Tsogbadrakh; Myadagsuren, Narankhajid

doi:10.1016/j.parepi.2023.e00318

Cited by 5 publications

(2 citation statements)

References 49 publications

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“…All positive samples were from one site in Sibiu County. Although the overall seroprevalence for Sibiu County was 4.9%, because all the positive samples were from one locality, the seroprevalence was 9.72% CI (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). We did not find any significant difference regarding potential risk factors for TBEV infection (see Table 3).…”

Section: Serum Neutralization Test Resultsmentioning

confidence: 70%

“…We aimed to obtain information on the distribution and epidemiology of TBEV subclinical infection in counties not only where cases of TBEV have been reported but also in other areas known as non-endemic but where I. ricinus has been identified as the dominant species of ticks. Also, we chose rural areas since the population might be at a higher risk of the disease than those living in urban areas (a fact that may be caused by differences in tick habitat and exposure risk, not only due to outdoor activities but also by a lack of awareness and preventive measures in rural areas) [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

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Serosurvey of Tick-Borne Encephalitis Virus Infection in Romania

Panciu,

Cheran,

Militaru

et al. 2024

Pathogens

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Background: Tick-borne encephalitis (TBE) is a disease with mandatory declaration in the EU since 2012. Information regarding the seroprevalence of the disease across Romania is limited, and only sporadic cases are rarely reported. We aimed to identify new areas of TBEV infection in different counties of Romania. Methods: We conducted a serosurvey assessing the immune response to TBEV infection in adult populations from rural areas in different counties of the country. Seropositivity was defined by a positive TBEV IgM/IgG ELISA test and confirmed by serum neutralization. Results: We collected 1116 samples from 15 different localities in 10 counties (divided into endemic/border/non-endemic counties) across Romania. Overall, 26 (2.3%) of the samples were tested positive using the TBEV ELISA assay in six counties. In those counties, 3.7% of sera were positive, varying from 1.4% to 6.9% per county. After performing the neutralization assay, seven (0.6%) samples were confirmed positive, interestingly all from one site in Sibiu County, where the seroprevalence was 9.7%. Conclusions: The identification of positive serum samples in serosurveys appears to rely on the discovery of TBEV microfoci. Further serological surveys should be conducted in Romania, especially after the identification of positive TBEV patients presenting for medical care.

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Section: Serum Neutralization Test Resultsmentioning

confidence: 70%

Section: Introductionmentioning

confidence: 99%

Serosurvey of Tick-Borne Encephalitis Virus Infection in Romania

Panciu,

Cheran,

Militaru

et al. 2024

Pathogens

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The Prevalence of Tick‐Borne Encephalitis Virus Infection Among Humans in Heilongjiang Province of China in 2020–2023

Chen,

Lu,

Wang

et al. 2024

Zoonoses and Public Health

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Background and AimsTick‐borne encephalitis (TBE) is a serious and acute central nervous system infection caused by the tick‐borne encephalitis virus (TBEV). In recent years, TBE has emerged as a growing public health threat, with cases reported across Europe, the Russian Far East, Japan and China. This study aims to assess the prevalence of TBEV infection and examine behaviours associated with an increased risk of infection among individuals who visited the Heilongjiang Red Cross Sengong General Hospital due to tick bites from 2020 to 2023.Methods and ResultsWe collected blood samples and administered survey questionnaires from tick‐bitten people. A total of 457 samples were screened using Nested PCR, and the detected TBEV prevalence rate was 29.54% (135/457). The symptoms of redness and swelling at the site of tick bite (42.57%), fever (28.71%) and headache (10.89%) were identified in the TBEV‐positive individuals when they visited the hospital by the physician. Phylogenetic analysis of the partial E gene of TBEV revealed that the predominant strains in the region are highly virulent Far Eastern subtype. However, they do not cluster with the three established evolutionary clades of the Far Eastern type. Questionnaires data analysis identified age and first tick bite as important factors associated with TBEV infection.ConclusionsThis study provides basic information on the epidemiology of TBEV in Heilongjiang Province in recent years and identifies that the most related risk factor of infecting TBEV is tick exposure. Further research is needed to develop effective prevention and control measures.

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