Seroprevalence and Risk of Toxoplasma gondii Infection among Pregnant Women at Federal Teaching Hospital Gombe, Nigeria

Ballah, Fatimah Muhammad; Maikai, B.V.; Magaji, A. A.; Shuaibu, Abdulmalik Bello; El-Nafaty, Aliyu Usman; Sambo, Yohanna; Auwal, A; Faruk, Husni; Suleiman, F

doi:10.9734/ajmah/2017/31528

Cited by 7 publications

(9 citation statements)

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“…Significant association was observed between previous occurrence of bad obstetric history and seropositivity to T. gondii antibodies in this study. This study result is in agreement with the study results obtained in Gombe State, Nigeria (Ballah et al, 2017) who observed an association with previous bad obstetric history. In consideration with types of bad obstetric histories and its association with prevalence rate of T. gondii, bad obstetric history such as history of previous miscarriages and congenital malformations were found significant.…”

Section: Discussionsupporting

confidence: 93%

“…This result portrays that oocyst can survive for long period in water hence individuals who drink untreated water maybe frequently exposed to T. gondii (Ishaku, et al, 2009). The presence of cats in the home has been attributed with significance with sero-prevalence of T. gondii infections (Alvarado, et al, 2006, Ballah et al, 2017. We observed in this study no significant association between cat ownership and sero-prevalence of T. gondii antibodies.…”

Section: Discussioncontrasting

confidence: 54%

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Seroprevalence of Toxoplasma Gondii Infection Among Pregnant Women Attending Antenatal Clinic in Major Health Centers in Jos North, Nigeria

Akubuilo¹,

Amali²,

Onekutu³

2020

OJBR

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Toxoplasmosis is an infection caused by Toxoplasma gondii. It is reported that one third of the world’s population is infected with the parasite. T. gondii represents the risk of miscarriages and congenital abnormalities in pregnancy. This study was carried out to ascertain the sero-prevalence of Toxoplasma gondii among pregnant women attending antenatal clinics in three major Health Centres in Jos North Local Government Area, Plateau State, Nigeria. Three hundred and eight four (384) pregnant women attending antenatal clinics were recruited for the study. Participants were screened for T. gondii specific antibodies using the Chromatographic Immuno-Assay (CIA) test method. Information on risk factors were obtained by the administration of a structured questionnaire. An overall seroprevalence of 11.7% was established. IgG antibodies represented 11.7% seroprevalence and 0.0% seroprevalence recorded for IgM antibodies. The highest seroprevalence of Toxoplasma gondii infection was established in women in their second trimester. Seropositivity was found to be significantly associated (p<0.05, 95%CI) with type of drinking water, consumption of raw or fresh vegetables, previous history of miscarriage and older child with congenital deformation. Akubuilo, A. S. | Department of Zoology, University of Agriculture Makurdi, Benue State, Nigeria

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Section: Discussionsupporting

confidence: 93%

Section: Discussioncontrasting

confidence: 54%

Seroprevalence of Toxoplasma Gondii Infection Among Pregnant Women Attending Antenatal Clinic in Major Health Centers in Jos North, Nigeria

Akubuilo¹,

Amali²,

Onekutu³

2020

OJBR

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“…It is similar to the finding of Jones et al that found seropositivity rate significantly higher in older women aged over 40 years [25]. However, this did not agree with the finding by Tammam et al and Ballah et al who found IgG seropositivity rates to be higher among pregnant women less than 20 years of age (52.86%) [28,30].…”

Section: Resultssupporting

confidence: 65%

Prevalence and Determinants of Toxoplasma Seropositivity among Women Who had Spontaneous Abortion in Gombe, North-Eastern Nigeria

Farouk

Manga

Yahaya

et al. 2020

JAMMR

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Aim: To determine the seroprevalence and determinants of Toxoplasma IgG and IgM seropositivity among women with spontaneous abortion in Gombe. Materials and Methods: This was a cross-sectional study of 302 pregnant women with spontaneous abortion, presenting at the gynaecological emergency units of Federal Teaching Hospital Gombe and State Specialist Hospital Gombe. An interviewer-administered questionnaire was used to collect data, and a venous blood sample was drawn from each participant and tested for Toxoplasma IgG and IgM by ELISA technique. Results: Toxoplasma seroprevalence was 62(20.5%) and was higher in women that owned cats (24% vs 20.1%, OR 1.3, 0.5-3.1) and ate grilled meat (suya) (21.0% vs 11.8%, OR 2.0, 0.4-9.0), but lower in those that washed fruits and vegetables before consumption (OR 0.6, 0.2-1.4). Conclusion: Seroprevalence of Toxoplasmosis in Gombe is high and may be influenced by cat ownership cooking and eating habit.

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“…In Nigeria it was determined that abortion occurred in 41.6% to 60% of pregnant women presenting anti-Toxoplasma antibodies, stillbirth happened in 6.8% to 61.5% of the cases, and neonatal death in 62.5%. Ocular problems occurred in 29.4% of newborns [60][61][62]. Torgerson and Mastroiacovo [63] estimated per 1000 live births the incidence of congenital cases accounting for 2-2.4 to 13-15 of all Disability-Adjusted Life Years (DALYs) for the African continent, despite several African countries have not reported cases of congenital toxoplasmosis or seroprevalence data.…”

Section: Toxoplasmosis In Neonates and Infantsmentioning

confidence: 99%

Human toxoplasmosis in Mozambique: gaps in knowledge and research opportunities

2020

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Toxoplasmosis is a parasitic zoonotic disease caused by Toxoplasma gondii that afflicts humans worldwide and wild and domestic warm-blooded animals. In immunocompetent individuals, the acute phase of infection presents transient low or mild symptoms that remain unnoticed. In immunocompromised patients, T. gondii is a life-threatening opportunistic infection, which can result from the reactivation of latent infection or primary infection. Moreover, congenital toxoplasmosis, which results from the transplacental passage of tachyzoites into the fetus during a pregnant primary infection, can lead to miscarriage, stillbirth, or ocular and neurologic disease, and neurocognitive deficits in the newborns. Thus, the present review aims to address the current knowledge of T. gondii infection and toxoplasmosis in Africa and especially in Mozambique, stressing the importance of identifying risk factors and promote awareness among the health care providers and population, assessing the gaps in knowledge and define research priorities. In Mozambique, and in general in southern African countries, clinical disease and epidemiological data have not yet been entirely addressed in addition to the implications of T. gondii infection in immunocompetent individuals, in pregnant women, and its relation with neuropsychiatric disorders. The main gaps in knowledge in Mozambique include lack of awareness of the disease, lack of diagnostic methods in health facilities, lack of genetic data, and lack of control strategies.

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Seroprevalence and Risk of Toxoplasma gondii Infection among Pregnant Women at Federal Teaching Hospital Gombe, Nigeria

Cited by 7 publications

References 0 publications

Seroprevalence of Toxoplasma Gondii Infection Among Pregnant Women Attending Antenatal Clinic in Major Health Centers in Jos North, Nigeria

Seroprevalence of Toxoplasma Gondii Infection Among Pregnant Women Attending Antenatal Clinic in Major Health Centers in Jos North, Nigeria

Prevalence and Determinants of Toxoplasma Seropositivity among Women Who had Spontaneous Abortion in Gombe, North-Eastern Nigeria

Human toxoplasmosis in Mozambique: gaps in knowledge and research opportunities

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