Seroprevalence of caseous lymphadenitis in goats sold in an animal fair in the northeastern semi-arid region of Brazil

Abstract

Goat farming in the northeastern regions of Brazil plays an important role in the socio-economic functions of the country. However, high rates of morbidity and mortality occur in the animals, caused primarily by infectious diseases like caseous lymphadenitis, which is widespread in goat herds; this causes serious economic losses to the farming business. Although events such as animal fairs are common in the region, wherein most of the goats and sheep are sold, the risk of disease transmission remains, since the health condition of the animal is unknown. The aim of this study was to determine the frequency of anti-Corynebacterium pseudotuberculosis antibodies present in the goats sold at the animal fair of Tabira -PE, Northeastern semi-arid. Serum samples from 233 goats were collected from the period of November 2014 to June 2015. The diagnosis of infection by C. pseudotuberculosis was made using the indirect ELISA technique. The number of goats seropositive for C. pseudotuberculosis was identified as 87 (37.34%; 95% CI = 31.38 -43.71%). Of the nine flocks evaluated, five (55.55%) were positive. Thus, it is suggested that infection by C. pseudotuberculosis is widespread in the goats sold at the animal fairs in the semi-arid Northeastern, reinforcing the need for disease diagnosis in goat herds in the region for the possible implementation of disease control programs. Key words: Agglomerations. Caseous lymphadenitis. Goats. Serology. ResumoA caprinocultura se destaca na região Nordeste do Brasil por desempenhar importante função socioeconômica. Contudo altas taxas de morbidade e mortalidade ocorrem nas propriedades causadas principalmente por doenças infecciosas, destacando-se a linfadenite caseosa, que se encontra amplamente difundida nos rebanhos caprinos, acarretando sérios prejuízos econômicos à atividade. Eventos do tipo

Ciências Rurais em Foco - Volume 10

“…Immunosorbent Assay) é um método versátil a ser usado nos programas de controle e erradicação em rebanhos. Estudos envolvendo ELISA indireto, contendo componentes do extrato bruto bacteriano e proteínas secretadas de C. pseudotuberculosis foram relatados por serem relativamente eficazes em programas de controle da enfermidade (FARIAS et al, 2018;ALVES et al, 2018). Além disso, pode ser útil em estudos de soroprevalência da enfermidade em rebanhos (OREIBY, 2015).…”

“…Além disso, os animais adultos têm maior contato com fontes de infecção por permanecerem mais tempo nos rebanhos e, portanto, maior chance de adquirir a doença(MACHADO et al 2011;SOUZA et al 2011) Souza et al, (2011). observaram que a maior prevalência reportada em fêmeas (17,9%), em comparação aos machos (13,8%), foi devido à maior idade de abate e maior período permanecido nas propriedades Alves et al, (2018). no município de Tabira -PE, observaram uma prevalência de 46,88% para fêmeas e de 14,44% para machos.…”

In silico functional prediction of hypothetical proteins from the core genome of Corynebacterium pseudotuberculosis biovar ovis

“…Caseous lymphadenitis entails harmful effects in the agribusiness globally, affecting the production of wool, meat and milk, besides diminishing the reproductive efficiency and condemning carcasses and skins of animals (Fontaine & Baird, 2008). In the Northeastern region of Brazil, C. pseudotuberculosis is responsible for infecting up to 37% of goats in animal farms, reinforcing the need for researches concerning this pathogen (Alves et al, 2018). Thus, it is necessary to perform in-depth research for the better comprehension of its biology, especially regarding to pathogenicity mechanisms-once the therapeutic methods current available are not completely effective, requiring prophylactic measures in order to combat proliferation and permanence of the pathogen into the hosts; however, those measures demand highly laborious processes (Lee, Hefta & Brennan, 1992).…”