Seroprevalence of Chronic Hepatitis B Virus Infection Among Taiwanese Human Immunodeficiency Virus Type 1–Positive Persons in the Era of Nationwide Hepatitis B Vaccination

Abstract

Our study showed a significant decline of seroprevalence of HBV infection among both HIV-negative and -positive persons who were born in the era of the nationwide HBV vaccination in Taiwan.

Molecular Epidemiology of Hepatitis D Virus Infection among Injecting Drug Users with and without Human Immunodeficiency Virus Infection in Taiwan

“…In Taiwan, the prevalence of chronic HBV infection is estimated to be 15 to 20% among individuals born before the implementation of a nationwide HBV vaccination program in 1984. In contrast to what has been observed in Western countries, we have found that the HBV seroprevalence among injecting drug users (IDU) is similar to that of other groups at risk for HIV transmission (32). Between 2003 and 2006, an outbreak of HIV infection and hepatitis C virus (HCV) infection occurred among IDU who shared needles and diluent in Taiwan (4,7).…”

Seroprevalence of hepatitis virus infection in men who have sex with men aged 18–40 years in Taiwan

“…In our previous study, the seroprevalence of HBsAg and anti-HBc was compared between HIV-positive and HIV-negative persons born before 1984. 17 Compared with HIV-negative persons born before July 1984, HIV-positive persons born before July 1984 had a significantly higher seroprevalence of HBsAg (20.3% vs. 15.5%, p < 0.001) and anti-HBc (78.9% vs. 72.1%, p < 0.001). 17 In addition, a significant decline in HBV seroprevalence among both HIV-negative and -positive persons born in the era of the nationwide HBV vaccination in Taiwan has also been shown.…”

“…17 Compared with HIV-negative persons born before July 1984, HIV-positive persons born before July 1984 had a significantly higher seroprevalence of HBsAg (20.3% vs. 15.5%, p < 0.001) and anti-HBc (78.9% vs. 72.1%, p < 0.001). 17 In addition, a significant decline in HBV seroprevalence among both HIV-negative and -positive persons born in the era of the nationwide HBV vaccination in Taiwan has also been shown. 17 In this study, positive antiHBs status alone, which indicates the prevalence of HBV vaccination-related protection, among HIV-negative and -positive MSM were 67.1% and 68.6%, respectively.…”

“…17 In addition, a significant decline in HBV seroprevalence among both HIV-negative and -positive persons born in the era of the nationwide HBV vaccination in Taiwan has also been shown. 17 In this study, positive antiHBs status alone, which indicates the prevalence of HBV vaccination-related protection, among HIV-negative and -positive MSM were 67.1% and 68.6%, respectively. Both rates are higher than that reported by Lu et al for persons of high-school or college age born after 1986 and received HBV vaccination at birth.…”

“…14e16 After an outbreak of HIV infection occurred among IDUs in Taiwan between 2003 and 2007, HCV seropositivity was 95e97% among HIV-positive IDUs. 9,14,17,18 While HCV transmission is significantly more efficient among IDUs than among MSM, an increasing number of reports have indicated that HCV infections are presenting among MSM who may be engaged in risky sexual contact. 19e27 In this study, we aim to compare the seroprevalence rates of HAV, HBV, and HCV between HIV-positive MSM and HIV-negative MSM aged between 18e40 years.…”