Seroprevalence of Cytomegalovirus Among Pregnant Women in Ad-Dhale'e City - Yemen

Binsaad, Adel Jumaan Awadh; Taleb, Arafat Abdo

doi:10.47372/ejua-ba.2022.2.159

Cited by 3 publications

(4 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a similar study, the high rate of HCMV infection was among pregnant women in the age group of 15-25 years [10] and 14-30 years [13]. This study is inconsistent because it documented that the high rate of HCMV infection was among pregnant women in the age group of 25-34 years (97.3%) [14] and 31-40 years [12]. In general, the frequency of HCMV is higher among women, people in older age brackets, people with lower socioeconomic status, and people in developing countries.…”

Section: Discussionmentioning

confidence: 96%

“…According to the current results, those who studied in secondary schools (46.2%) had the highest rate of HCMV prevalence. Different studies found a high proportion of HCMV infections in pregnant women with basic levels of education [10,14]. In terms of gestational stage, pregnant women experienced the highest rate of HCMV infection in their second trimester (65.4%).…”

Section: Discussionmentioning

confidence: 99%

“…As a result of HCMV infection or immune-mediated destruction, a foetus can suffer direct or indirect damage, including miscarriage, preterm birth, or fetal growth restriction [8]. According to reports, the prevalence of HCMV in pregnant women in Yemen was recorded at 100% in Sana'a [9], 98.7% in Hodeidah [10], 68% in Ibb [11], 75.79% in Yarim [12], 99% in Taiz [13], and 93.8% in Ad-Dhale'e [14].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effects of Human Cytomegalovirus on Some Hematological Parameters and Liver Function in Pregnant Women, Yemen

Al-Halani,

Edrees,

Al-Awar

et al. 2024

Preprint

View full text Add to dashboard Cite

Background Human Cytomegalovirus (HCMV) infection is a common congenital infection that affects approximately 0.7–1% of all live births worldwide. Approximately 11% of newborns who are infected show symptoms at birth, and of these, between 30% and 40% are at a risk of experiencing long-term neurological complications. This study aimed to evaluate the effect of HCMV on hematological parameters and liver function in pregnant women in Hajjah governorate, Yemen. Materials and Methods This study is a cross-section study that conducted in the Hajjah governorate of Yemen during a period of March to June 2023. A total of 108 blood specimens were collected from participants; 78 from patients group and 30 health group. Hematological parameters, such as total red blood cell count (RBC), hemoglobin (HB), platelet count (PLT), and white blood cells (WBC), as well as liver function tests, such as total protein, albumin, alkaline phosphatase (ALP), serum glutamic oxaloacetic transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), total bilirubin, and direct bilirubin, were measured. Results Majority of participant patients aged between 16–21 years 27 (34.7%), studied at secondary schools (46.2%), in their second trimester 51 (65.4%), those with multigravida 54 (69.2%), and those with no history of congenital diseases 60 (76.9%). Compared with the control group, the mean WBC levels were significantly lower in HCMV patients (P < 0.05), whereas PLT Levels were higher among HCMV patients (P < 0.05). Additionally, the mean levels of total bilirubin, direct bilirubin, SGOT, ALP, and albumin were significantly lower in patients with HCMV than in HC (P < 0.05). Furthermore, there were no significant differences between the patient and healthy groups in terms of HB, RBC counts, SGPT, and total protein (P > 0.05). Conclusion It can be concluded that HCMV infection had a statistically significant effect on WBC, PLT, total bilirubin, direct bilirubin, SGOT, ALP, and albumin levels in pregnant women. Consequently, further studies are needed to define the role of HCMV in liver disorders.

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of Human Cytomegalovirus on Some Hematological Parameters and Liver Function in Pregnant Women, Yemen

Al-Halani,

Edrees,

Al-Awar

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…CMV belongs to the subfamily Betaherpesvirinae and is recognized as the most common congenital viral infection in humans, with an estimated global seroprevalence of 83% (95% uncertainty interval [UI], 78 to 88) ( 4 ). There are, however, regions with reported CMV seroprevalences in adults of up to 100% ( 5 ). EBV, which infects 90 to 95% of humans worldwide, is a gammaherpesvirus and is the causative agent of infectious mononucleosis ( 6 ).…”

Section: Introductionmentioning

confidence: 99%

Performance Evaluation of the Fully Automated NeuMoDx RT-PCR Platform for the Quantification of CMV and EBV DNA in EDTA Plasma: Implications for Clinical Management and Establishment of a Conversion Formula

Herdina

Ratzinger²,

Breuer

et al. 2022

Microbiol Spectr

View full text Add to dashboard Cite

Clinical management of solid organ transplant (SOT) patients requires the careful monitoring of immunosuppression and viral infection or reactivation. qPCR is the gold standard for the detection and quantification of very small amounts of viral DNA and allows for an early assessment of viral load kinetics. The tested NeuMoDx 96 platform provides faster results than the previously used RT-PCR workflows for CMV (Abbott m2000 and RealTime CMV assay) and EBV (LightCycler 480 II, Roche high pure extraction, and Altona RealStar EBV assay) DNA detection.

show abstract

Seroprevalence of cytomegalovirus antibodies among aborted women in Ibb city-Yemen

Abbas¹,

AL-Moliki²,

Al-Zafri³

et al. 2022

JHVRV

View full text Add to dashboard Cite

Abortion is one of the most common health problems in the world, its causes vary, and some of them are viral. Cytomegalovirus (CMV) is one of the causes of abortion. So, this study aims to investigate the seroprevalence of CMV antibodies among aborted women. This study was a cross-sectional study conducted in Ibb city-Yemen. Serum samples were collected between September 2021 to April 2022. The serum samples were analyzed for IgG and IgM antibodies to CMV by Electro-Chemiluminescence Immunoassay (ECLIA). Overall, 150 aborted women were enrolled. Amongst these cases, 148 out of 150 (98.67%) were positive for CMV IgG antibodies. Additionally, 11 out of 150 (7.33%) of the samples were positive for CMV IgM antibodies. The CMV IgG seroprevalence was not significantly influenced by age, residence, education level, socioeconomic status and abortion time. In addition, the CMV IgM seroprevalence was significantly associated with education level, socioeconomic status and abortion time. In conclusion, the low rate of CMV IgM and a high proportion of CMV IgG for most major of abortion women in this study suggest that CMV may not be the common factor leading to abortion.

show abstract

Seroprevalence of Cytomegalovirus Among Pregnant Women in Ad-Dhale'e City - Yemen

Cited by 3 publications

References 23 publications

Effects of Human Cytomegalovirus on Some Hematological Parameters and Liver Function in Pregnant Women, Yemen

Effects of Human Cytomegalovirus on Some Hematological Parameters and Liver Function in Pregnant Women, Yemen

Performance Evaluation of the Fully Automated NeuMoDx RT-PCR Platform for the Quantification of CMV and EBV DNA in EDTA Plasma: Implications for Clinical Management and Establishment of a Conversion Formula

Seroprevalence of cytomegalovirus antibodies among aborted women in Ibb city-Yemen

Contact Info

Product

Resources

About