Seroprevalence of Dengue Viral Infection among Adults Attending the University of Cape Coast Hospital

Aniakwaa-Bonsu, Ebenezer; Amoako-Sakyi, Daniel; Dankwa, Kwabena; Prah, James Kojo; Nuvor, Samuel Victor

doi:10.4236/aid.2021.111008

Cited by 2 publications

(1 citation statement)

References 19 publications

(23 reference statements)

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“…However, there is a high risk due to the closeness and high density of the Aedes mosquito population in the country. In 2019, the last serological detection of DENV was reported in a study involving adults attending a secondary hospital in the Central Region [ 39 ]. The first suspected transmission of DENV via serology was reported after the isolation of DENV-2 from Finnish travelers who visited Ghana in 2005 [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

Arbovirus Epidemiology: The Mystery of Unnoticed Epidemics in Ghana, West Africa

et al. 2022

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It is evident that all the countries surrounding Ghana have experienced epidemics of key arboviruses of medical importance, such as the recent dengue fever epidemic in Burkina Faso. Therefore, Ghana is considered a ripe zone for epidemics of arboviruses, mainly dengue. Surprisingly, Ghana never experienced the propounded deadly dengue epidemic. Indeed, it is mysterious because the mosquito vectors capable of transmitting the dengue virus, such as Aedes aegypti, were identified in Ghana through entomological investigations. Additionally, cases may be missed, as the diagnostic and surveillance capacities of the country are weak. Therefore, we review the arbovirus situation and outline probable reasons for the epidemic mystery in the country. Most of the recorded cases of arbovirus infections were usually investigated via serology by detecting IgM and IgG immunoglobulins in clinical samples, which is indicative of prior exposure but not an active case. This led to the identification of yellow fever virus and dengue virus as the main circulating arboviruses among the Ghanaian population. However, major yellow fever epidemics were reported for over a decade. It is important to note that the reviewed arboviruses were not frequently detected in the vectors. The data highlight the necessity of strengthening the diagnostics and the need for continuous arbovirus and vector surveillance to provide an early warning system for future arbovirus epidemics.

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Section: Discussionmentioning

confidence: 99%

Arbovirus Epidemiology: The Mystery of Unnoticed Epidemics in Ghana, West Africa

et al. 2022

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Dengue fever outbreak in Puntland State, Somalia, November 2022-May 2023

Jama,

Abshir,

Jama

et al. 2023

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Dengue infection is a mosquito-borne, endemic viral disease, particularly in developing countries. Here, we report the results of the clinicodemographic, serologic profile, and monthly occurrence of a recent dengue fever outbreak in Puntland State (Somalia). We analyzed the data of 956 dengue-suspected patients who were investigated using the rapid diagnostic testing (RDTs) method for detecting NS1 (dengue virus non-structural protein) and IgM antibodies employing the SD Biosensor Dengue Dou NS Ag and IgM test kit (Germany) at the Puntland Public Health Referral Laboratory in the period from November 21, 2022, to May 27, 2023. We found that 118 cases were positive for dengue among the suspected patients enrolled in the present study. Of these cases, 86.4% were dengue NSI positive, and 23.7% were dengue IgM positive. The number of females and males in the confirmed cases was equal, and most (48.3%) were aged 20 years or less. 43.1% of them lived in the Nugal region, particularly in Garowe. Clinically, fever was the most frequent symptom (88.9%). The cases peaked in December 2022 but dropped from January to March, with a slight rise in February, and then increased in April and May 2023. We recommend improving vector control measures, strengthening dengue surveillance, developing an early warning system, and future studies to characterize the circulating strains.

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Seroprevalence of Dengue Viral Infection among Adults Attending the University of Cape Coast Hospital

Cited by 2 publications

References 19 publications

Arbovirus Epidemiology: The Mystery of Unnoticed Epidemics in Ghana, West Africa

Arbovirus Epidemiology: The Mystery of Unnoticed Epidemics in Ghana, West Africa

Dengue fever outbreak in Puntland State, Somalia, November 2022-May 2023

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