Seroprevalence of dengue virus in a tertiary care hospital, Andhra Pradesh, South India

Rao, Srinivas; Pavani, K; Dass, Manick; Kareem, Mohamed Abdul; Vinayaraj, E V

doi:10.5455/2320-6012.ijrms20131127

Cited by 6 publications

(1 citation statement)

References 10 publications

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“…The prevalence rate of 17.2% from this study is lower than what Faneye et al (2013) who reported 30.8% among the population studied in Nigeria. Likewise it is also lower than that of Srinivas et al, (2013) who recorded 17.7% prevalence. Baba et al (2009) reported 0.6% IgM seropositivity which is lower than the results from this study.…”

Section: Discussionmentioning

confidence: 56%

Detectable Anti-Dengue Virus Igm Antibodies Among Healthy Individuals in Ogbomoso, Oyo State, Nigeria

Oladipo

Amanetu

Gbadero

et al. 2014

American Journal of Infectious Diseases

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Dengue fever is a zoonosis maintained in nature by mosquitoes transmitting virus between non-human primate species, most of which develop clinically in apparent infection. It has been found to be endemic in Africa and beyond. A survey for Dengue virus IgM antibody was carried out in Ogbomoso (urban and rural areas) using Enzyme Linked Immunosorbent Assay (WKEA Med Supplies Corp, Dengue fever virus ELISA Kit (China),) to determine the seroprevalence and true incidence of dengue virus in Ogbomoso. A total of 186 apparently healthy individuals were recruited into the study. The sera of 93 subjects who consented to participate were collected. The mean age of the subjects tested was 37.6±0.67. Anti-Dengue virus IgM antibodies were found in 16/93, (17.2%). The highest prevalence of anti-Dengue 28.6% was found in persons whose ages were between 0-15 years, males (18.9%), civil servants (26.3%) and urban dwellers (21.3%). The findings from this study show that there is primary infection of this virus in Ogbomoso and suggest the need for preventive and control measures against dengue fever virus.

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Section: Discussionmentioning

confidence: 56%

Detectable Anti-Dengue Virus Igm Antibodies Among Healthy Individuals in Ogbomoso, Oyo State, Nigeria

Oladipo

Amanetu

Gbadero

et al. 2014

American Journal of Infectious Diseases

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Dengue infection in India: A systematic review and meta-analysis

et al. 2018

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IntroductionDengue is the most extensively spread mosquito-borne disease; endemic in more than 100 countries. Information about dengue disease burden, its prevalence, incidence and geographic distribution is critical in planning appropriate control measures against dengue fever. We conducted a systematic review and meta-analysis of dengue fever in IndiaMethodsWe searched for studies published until 2017 reporting the incidence, the prevalence or case fatality of dengue in India. Our primary outcomes were (a) prevalence of laboratory confirmed dengue infection among clinically suspected patients, (b) seroprevalence in the general population and (c) case fatality ratio among laboratory confirmed dengue patients. We used binomial–normal mixed effects regression model to estimate the pooled proportion of dengue infections. Forest plots were used to display pooled estimates. The metafor package of R software was used to conduct meta-analysis.ResultsOf the 2285 identified articles on dengue, we included 233 in the analysis wherein 180 reported prevalence of laboratory confirmed dengue infection, seven reported seroprevalence as evidenced by IgG or neutralizing antibodies against dengue and 77 reported case fatality. The overall estimate of the prevalence of laboratory confirmed dengue infection among clinically suspected patients was 38.3% (95% CI: 34.8%–41.8%). The pooled estimate of dengue seroprevalence in the general population and CFR among laboratory confirmed patients was 56.9% (95% CI: 37.5–74.4) and 2.6% (95% CI: 2–3.4) respectively. There was significant heterogeneity in reported outcomes (p-values<0.001).ConclusionsIdentified gaps in the understanding of dengue epidemiology in India emphasize the need to initiate community-based cohort studies representing different geographic regions to generate reliable estimates of age-specific incidence of dengue and studies to generate dengue seroprevalence data in the country.

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Seroprevalence of dengue in the tribal district of central India

Madkey¹,

Gedam²,

Meshram³

et al. 2021

IJMR

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Background: Dengue is a vector-borne disease that is a major public health threat globally affecting three billion people with approximately 200 million cases of morbidity and 50,000 cases of mortality annually. It is transmitted to humans by Aedes mosquitoes. It is caused by the dengue virus (DENV, 1-4 serotypes). The clinical manifestations of dengue vary from mild fever to severe hemorrhage, shock, and death. It is critical to make an early and accurate laboratory diagnosis of DENV infection for effective patient management. Dengue is now no more restricted to the urban population, it has become endemic in the rural population as well. Aim and Objectives: 1. To find the seroprevalence of dengue virus infection in the tribal population of Gondia district. 2. To observe the seasonal variation of dengue cases. Materials and Methods: This study was conducted under the NVBDC program at the Department of Microbiology, GMC, Gondia which is the sentinel center for Dengue and Chikungunya. The Study was carried out from October 2018 to September 2020. Serum samples of patients with dengue-like clinical illness were subjected to IgM antibody detection by dengue MAC ELISA. Results: Seroprevalence of dengue in Gondia was found to be 12.37% (48/388). The most common age group affected was 21-30 years (39.59%). Males (54.17%) were affected more than females (45.83%). The peak of dengue cases was observed in September 2019. Less number of cases were reported in the year 2020. Conclusion: Newer diagnostic techniques, public awareness programs, better education, and proper monitoring of vector control are required to prevent dengue outbreaks.

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Seroprevalence of dengue virus in a tertiary care hospital, Andhra Pradesh, South India

Cited by 6 publications

References 10 publications

Detectable Anti-Dengue Virus Igm Antibodies Among Healthy Individuals in Ogbomoso, Oyo State, Nigeria

Detectable Anti-Dengue Virus Igm Antibodies Among Healthy Individuals in Ogbomoso, Oyo State, Nigeria

Dengue infection in India: A systematic review and meta-analysis

Seroprevalence of dengue in the tribal district of central India

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