Seroprevalence of hepatitis E virus infection in pregnant women: a systematic review and meta-analysis

Abstract

Seroprevalence of hepatitis E virus infection in pregnant women: a systematic review and meta-analysis.

Seroprevalence of Hepatitis E Virus Infection in Middle Eastern Countries: A Systematic Review and Meta-Analysis

“…Worldwide, seroprevalence-based studies have received increased attention in recent years. However, due to incorrect diagnosis, underestimation, and a lack of awareness among clinicians about HEV, the published literature contains considerable gaps [ 94 , 95 ]. As a result, the goal of this study was to determine the seroprevalence of HEV infection in ME countries.…”

“…However, in our study, in the fixed-effect and random-effect models, the overall pooled seroprevalence of HEV infection in ME countries was 21.3% and 11.8%, respectively. According to a recent systematic review and meta-analysis, the overall pooled prevalence of HEV infection in pregnant women around the world was 16.51% [ 95 ]. A systematic review of HEV seroprevalence in thirteen African nations found that it ranged from zero to eighty-four percent, with pregnant women and rural areas having higher immunoglobulin levels than other areas [ 96 ].…”

Low Prevalence of HEV Infection and No Associated Risk of HEV Transmission from Mother to Child among Pregnant Women in Vietnam

“…In Vietnam—a country where HEV and HBV infections are endemic—pregnant women are at high risk of HEV infection, which is often caused by HEV genotype 1 (HEV-1). However, there is little literature on the seroprevalence of HEV in pregnant women, particularly in Vietnam and South-East Asia, where HEV genotype 3 (HEV-3), followed by HEV genotype 4 (HEV-4), have been reported as the predominant HEV genotypes [ 17 ]. Little is known about infections caused by the HEV-3 genotype during pregnancy and their clinical consequences [ 9 , 18 ].…”

“…Moreover, acute liver failure—a severe consequence of HEV infection in pregnant women—is rare in those with HEV-3 or -4 genotypes, and observed mostly in persons with HEV-1 or pre-existing liver diseases [ 20 , 21 ]. HEV genotype 1 (HEV-1) is transmitted via the oral–fecal route, as opposed to zoonotic transmission of HEV genotype 3 (HEV-3) [ 9 , 17 , 22 , 23 , 24 ].…”

Seroprevalence of hepatitis E virus (<i>Hepeviridae: Orthohepevirus: Orthohepevirus A</i>) among pregnant women in the highly endemic region of Kyrgyzstan

“…1,1-3,0 3,1-5,0 5,1-7,0 7,1-9,0 9,1-10,0 1,1-3,0 3,1-5,0 5,1-7,0 7,1-9,0 Согласно полученным результатам, в обследованных регионах Кыргызстана у беременных серопревалентность ВГЕ по IgG-антителам составляет 5,97%, по IgМ-антителам -4,82%. Эти данные соответствуют результатам метанализа распространённости IgG-антител к ВГЕ у беременных, согласно которым выявляемость IgG-антител к ВГЕ в разных регионах в среднем составляет 16,51% [25], при этом в странах Ближнего Востока, близких к изучаемому региону, она схожа с полученными нами значениями: в Пакистане -8,86%, в Иране -6,2%. Данные по частоте обнаружения IgM-антител у населения гиперэндемичных регионов ограничены.…”