Seroprevalence of Herpes Simplex virus types 1 and 2 and their association with CD4 count among HIV-positive patients

Abstract

Background: Herpes simplex virus (HSV) is a common cause of viral opportunistic infections among HIV t-tests and analysis of variance (ANOVA). Results: There were no significant differences in HSV-1 seroprevalence between HIV-positive patients (71%) and HIV-negative patients (66%). HSV-2 seroprevalence was significantly higher in HIV-positive patients (30%) than HIV-negative patients (5%). The titers of HSV-1 IgG antibodies in HIV-positive patients (mean 24.63 ± 19.06 IDU) were significantly lower than those of HIV-negative patients (mean 44.62 ± 33.22 IDU). In contrast, HSV-2 IgG antibody titers in HIV-positive patients (mean 13.31 ± 20.28 IDU) were significantly higher than HIV-negative patients (mean 4.42 ± 10.99 IDU)