Seroprevalence of HIV-1 and Syphilis Antibodies in Blood Donors in Gonder, Ethiopia, 1989???1993

Assefa, Abraham; Rahlenbeck, Sibylle I.; Molla, Kassie; Alemu, Shitaye

doi:10.1097/00126334-199412000-00010

Cited by 10 publications

(11 citation statements)

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“…Nearly a decade ago, Rahlenbeck SI et al (7) reported a 16.7% prevalence of HIV infection among Ethiopian blood donors. Another local research work from Gondar showed crude seroprevalence of HIV was 10.6% in men and 11.9% in women among a similar study population which is in parallel with our finding (8).…”

Section: Discussionsupporting

confidence: 91%

Seroprevalence of major blood-borne infections among blood donars at Felege Hiwot referral hospital, Northwest Ethiopia

Dessie¹,

Abera²,

Wale³

2007

Ethiopian Journal of Health Development

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A cross-sectional study was conducted to determine the seroprevalence of major transfusion-transmissible infections among blood donors at Felege Hiwot referral hospital, northwest Ethiopia. The overall seroprevalence of major bloodborne pathogens among blood donors was 43.2%, of which HBsAg, anti-HCV IgG, HIV seropositivity and syphilis accounted for 25%, 13.3%, 11.7% and 1.2% respectively. Crude seroprevalence of major blood born pathogens was significantly higher in commercial blood donors (56.6%) compared to voluntary (17.6%) and replacement blood donors (53.6%) (p=0.0001). IntroductionAlthough blood transfusion is one of the known therapeutic interventions that cut across a number of clinical disciplines, the practice is not without risks. In Africa, about 10-15 % of HIV transmission had been related to blood transfusions (1) .The highest risk groups are children suffering from malaria and anaemia; women with pregnancy-related haemorrhage and victims of major trauma.

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Section: Discussionsupporting

confidence: 91%

Seroprevalence of major blood-borne infections among blood donars at Felege Hiwot referral hospital, Northwest Ethiopia

Dessie¹,

Abera²,

Wale³

2007

Ethiopian Journal of Health Development

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“…In a study of 21 846 serum samples from blood donors collected between 1987 and 1989 from five major cities in Ethiopia, sex-specific RPR reactivity was 3 % in females [22]. In Gondar, we had reported an increasing rate of 2, 6n5 and 9n3 % RPR reactivity rate among women blood donors for the years 1991-3 [3]. The current prevalence of 17n2 % for TPHA, 14n8 % for RPR and 7n3 % for RPR and TPHA among ANC attenders in Gondar indicates that syphilis is still a major health problem in the area and underlines the importance of antenatal screening to prevent congenital syphilis.…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of HIV among female blood donors in Gondar [3] had increased from 7 % in 1989 to 16n8 % in 1992 and decreased to 13n4 % in 1993. When controlled for year and age, seroprevalence was not significantly different from men.…”

Section: Discussionmentioning

confidence: 99%

“…The HIV epidemic is spreading quickly in Ethiopia [1]. Although urban areas still account for most of the infection, with the highest prevalence seen among female sex workers, soldiers and drivers [2], seropositivity is increasing rapidly among the general population [3] and the gap between so-called high risk groups and the sexually-active adult population is narrowing. Reports indicate that the virus is infiltrating into rural areas where the vast majority ( 80 %) of the Ethiopian population resides [4,5].…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of HIV, syphilis and genital chlamydial infection among women in North-West Ethiopia

et al. 1998

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The prevalence of sexually transmitted diseases (STD) among women visiting antenatal (ANC) and gynaecological clinics in Gondar, north-west Ethiopia, was investigated. Between April and August 1995, 728 women consented to enter the study. Prevalence rates were 5.9% (41/693) for chlamydial antigen in cervix, 18.8% (113/600) for syphilis (Treponema pallidum haemagglutination assay [TPHA]) and 25.3% (150/593) for HIV. Active syphilis (RPR)+, TPHA+ was detected in 74% (44/597). HIV infection rate was higher among women with higher age of first marriage and low gravidity. It was significantly associated with young age, urban residence, and presence of genital ulcer (odds ratio [OR] = 6.3), and lymphadenopathy (OR = 2.8) on examination. Women seropositive for syphilis had married at an earlier age, were significantly older and had changed husbands. Low gravidity and age < 30 were independently significant risk factors for cervical chlamydial antigen positivity which was predominantly asymptomatic. Significant association was observed between HIV infection and syphilis (OR = 2.6). Active syphilis was associated with chlamydial (OR = 3.4) and HIV infection (OR = 4.1). The rate of 23.4% and 15.1% of HIV seropositivity among ANC attenders and rural women respectively is an indicator of the rapid progression of the HIV epidemic in the area.

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“…[6][7][8][9] Treponematoses other than syphilis infections are uncommon in this part of Ethiopia, 10 and thus unlikely to contribute to this high figure. As expected, past/current syphilis was associated with markers of risky sexual behaviours in both sexes, including HIV and HSV-2 infections.…”

Section: Discussionmentioning

confidence: 99%

Low incidence of syphilis among factory workers in Ethiopia: effect of an intervention based on education and counselling

Sahlu

2002

Sexually Transmitted Infections

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Background: The prevalence and incidence of syphilis infection were examined in a cohort study of factory workers in Ethiopia. Method: Between February 1997 and March 1999, 409 men and 348 women were enrolled and followed in the cohort study. Results: The prevalence (95% CI) of past/current syphilis (positive TPPA serology) was 28.9% (25.7% to 32.3%), and factors associated with past/current syphilis were markers of risky sexual behaviours including HIV infection. In this cohort of factory workers subject to public information/education meetings, testing for HIV antibodies, and individual counselling, the incidence (97.5% one sided CI) of new syphilis infections was 0/691 = 0 (0 to 0.5) per 100 person years. Conclusion: This study has documented a reduction in risky sexual behaviours and a low syphilis incidence among factory workers participating in a cohort study on HIV infection progression in Addis Ababa

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Seroprevalence of HIV-1 and Syphilis Antibodies in Blood Donors in Gonder, Ethiopia, 1989???1993

Cited by 10 publications

References 0 publications

Seroprevalence of major blood-borne infections among blood donars at Felege Hiwot referral hospital, Northwest Ethiopia

Seroprevalence of major blood-borne infections among blood donars at Felege Hiwot referral hospital, Northwest Ethiopia

Prevalence of HIV, syphilis and genital chlamydial infection among women in North-West Ethiopia

Low incidence of syphilis among factory workers in Ethiopia: effect of an intervention based on education and counselling

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