BACKGROUNDTransfusion Transmissible Infections (TTIs) like HIV, HBV, HCV, syphilis and malaria are major problems associated with blood transfusion practices. Because of shared modes of transmission, co-infection with HIV, HBV and HCV is a significant occurrence. Apparently, healthy blood donors may carry double viral co-infections that might be more fatal than viral mono-infection for the donor himself as well as recipient later on. Hence the study was undertaken to analyse the prevalence and patterns of coinfections among blood donors in our geographical area.