2023
DOI: 10.1371/journal.pone.0288015
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Seroprevalence of non-typhoidal Salmonella disease and associated factors in children in Mukuru settlement in Nairobi County, Kenya

Abstract: Non-typhoidal Salmonella (NTS) infections remain a significant public health challenge especially in sub-Saharan Africa. NTS disease is endemic in Kenya and is associated with sporadic fatal outbreaks in several regions of the country with poor resource setting. Data is limited on background exposure of NTS in the population in endemic areas and the general immune status of the community most affected by NTS. The aim of the study was to determine the proportion of children exposed to Salmonella Enteritidis or … Show more

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Cited by 2 publications
(2 citation statements)
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“…Prolonged faecal bacterial shedding lasting longer than a month may accompany these symptoms. The most prevalent type of NTS infection, gastroenteritis, is thought to cause 93.8 million cases and 155,000 fatalities worldwide each year ( Peter et al ., 2023 ). According to monitoring data from 2001 to 2005, S. enterica (12%) is the most commonly isolated serovar that causes NTS infections globally, followed by S. Typhimurium (4%) from clinical isolates that have been recovered ( Kumar et al ., 2022 ).…”
Section: Nomenclaturementioning
confidence: 99%
“…Prolonged faecal bacterial shedding lasting longer than a month may accompany these symptoms. The most prevalent type of NTS infection, gastroenteritis, is thought to cause 93.8 million cases and 155,000 fatalities worldwide each year ( Peter et al ., 2023 ). According to monitoring data from 2001 to 2005, S. enterica (12%) is the most commonly isolated serovar that causes NTS infections globally, followed by S. Typhimurium (4%) from clinical isolates that have been recovered ( Kumar et al ., 2022 ).…”
Section: Nomenclaturementioning
confidence: 99%
“…NTS is responsible for 93.8 million gastroenteritis cases each year, with 155 thousand deaths globally [11]. Invasive non-typhoidal Salmonella (iNTS) infections are characterized by abdominal pain, diarrhoea, nausea, vomiting and fever [12]. In immune-compromised individuals, iNTS is responsible for causing bacteraemia or focal infections at systemic sites [11].…”
Section: Introductionmentioning
confidence: 99%