Seroprevalence of rubella virus among pregnant women: A 4‐year registered‐based study from family medicine and obstetric clinics in Saudi Arabia

AlShamlan, Nouf A; AlOmar, Reem S; Alotaibi, Amani; Almukhadhib, Omar Y; AlShamlan, Abeer A; Alreedy, Abdullah; Zabeeri, Najwa; Darwish, Magdy A; Shammri, Malak A Al

doi:10.1111/ijcp.14156

Cited by 3 publications

(3 citation statements)

References 16 publications

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“…22 In 2020, one study in western part of Saudi Arabia showed that 88.9% of women are immune to rubella and another study showed that rubella susceptibility in women was as high as 24%. 23 , 24 Furthermore, WHO report 62 rubella cases in Saudi Arabia in 2019 along with 4 cases of congenital rubella syndrome in the period 2017–2018. 22 Therefore this study was done to determine the seroprevalence of rubella in the eastern province of Saudi Arabia and report cases of acute rubella infections to guide and assess national vaccination programs.…”

Section: Discussionmentioning

confidence: 99%

Susceptibility to Rubella Infection and Incidence of Congenital Rubella Infection: 6 Years Retrospective Study

Dossary¹,

Althuwaiqeb²,

Alkharsah³

et al. 2022

IJGM

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Introduction Rubella is considered one of the most serious and most common congenital infections. Despite global efforts for elimination, rubella cases are still being reported in many parts of the world. The purpose of this study is to determine the level of immunity to rubella in the community and most importantly among women at childbearing age in the eastern province of Saudi Arabia and compare it with the target set by the World Health Organization (WHO) along with the incidence of acute rubella infection and the associated congenital rubella infection and congenital rubella syndrome. Methods This is a retrospective cross-sectional study over the six years period (Jan 2014–Jun 2020) on all individuals tested for rubella IgM and IgG in a university teaching hospital. Results Nighty one percent (15,894/17,469) of the population tested showed evidence of rubella immunity with 8.8% (1546/17,469) being susceptible. Among women at childbearing age, susceptibility to rubella was higher with 9.2% (1220/13,278) of women showing no evidence of immunity. In addition, acute rubella infection was reported for 0.17% (29/17,469) of the population tested and 0.15% (20/13,278) in women at childbearing age. No cases of congenital rubella infection were reported in the study period. Discussion The level of Rubella immunity in the population is 91% and is less than the WHO target for rubella control therefore, risk of resurge of cases is present, indicating the need for continued national surveillance and more efforts to improve vaccination coverage in the kingdom.

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Section: Discussionmentioning

confidence: 99%

Susceptibility to Rubella Infection and Incidence of Congenital Rubella Infection: 6 Years Retrospective Study

Dossary¹,

Althuwaiqeb²,

Alkharsah³

et al. 2022

IJGM

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“…Jonas et al reported in a survey of women of reproductive age in Namibia that rubella antibody seroprevalence was higher in urban residents than in rural residents [ 19 ]. AlShamlan et al reported in a survey of pregnant women in Saudi Arabia that rubella antibody seroprevalence decreases with increasing age [ 20 ]. Liu et al reported in a survey of women preparing for pregnancy in rural China that women in regions with the low gross domestic product (GDP) per capita were more likely to be susceptible to rubella than women in regions with high GDP per capita [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

Factors Predicting Rubella Vaccination and Antibody in Pregnant Women in Japan: A Report from Pregnant Women Health Initiative

et al. 2022

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This study aimed to identify the factors predicting rubella vaccination status based on self-reported data and the presence of sufficient rubella antibody titers in pregnant women in Japan. We used the results of the nationwide questionnaire survey conducted at obstetric facilities in the Pregnant Women Health Initiative Project (PWHI), with 23 participating hospitals recruiting pregnant women from June 2018–November 2019. We extracted age, the number of deliveries, educational level, household income, pre-pregnancy smoking, and knowledge of rubella from questionnaires and medical records. We analyzed the association of rubella vaccination status and antibodies with each of these factors. We found that the number of previous deliveries, educational level, annual household income, smoking before pregnancy, and knowledge of rubella were factors predicting self-reported rubella vaccination status, while age and the number of previous deliveries were identified as factors predicting the presence of sufficient rubella antibody titers (32 folds or higher). Women considering pregnancy should be immunized against rubella to prevent congenital rubella syndrome in the future. Furthermore, social policies are needed to strongly encourage vaccination, especially for all citizens who were not given the opportunity or missed the chance to be vaccinated against rubella.

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“…Rubella is caused by the rubella virus, an enveloped, single-stranded, positive-sense Paramyxo-virus R.N.A. virus that is the only member of the genus Rubivirus [5] . Rubella is usually a mild disease that subsides on its own.…”

Section: Introductionmentioning

confidence: 99%

Study the changes in vitamin D3, magnesium, phosphorus, parathyroid hormone and calcium levels among women positive for SARS-2 n COVID-19 concerning rubella infection

Tahseen

Amin

Ali

et al. 2022

ijhs

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Background: After February 2020, SarsnovelCovid-19 became pandemic; therefore, Iraqi people were implicated in this enigma. Rubella infection in women in Kirkuk Provence as Bad Obstetric History (BOH) was more common. Suspecting co-infection for these two viruses' infections and the changes in the women's body like Vitamin D, Calcium, Magnesium, and other biochemical changes. Aims: this current study was carried on to assess and grant that. Setting: a cross-sectional observational study on 154 women of childbearing age with approved SARS n-covid-19 by real-time PCR was enrolled as a test group. Versus 45 women negative for covid with previous BOH were taken as a control group, and their ages ranged from 15 to 50 years. Methodology: Rubella IgM and IgG antibodies using ELISA kits were used for each woman. Vitamin D3, Parathyroid hormone (PTH) ELISA kit also used. For determining serum Calcium, Magnesium, and Phosphorus, routine spectrophotometry biochemical kits were tested. Results: The rate of Rubella infection was 77.92% IgG, contributed to 77.92 % of Rubella IgM versus 72.27 %. Controversy to the following rates 35.56 % and 8.88% of IgG and IgM respectively, P<0.05.

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Seroprevalence of rubella virus among pregnant women: A 4‐year registered‐based study from family medicine and obstetric clinics in Saudi Arabia

Cited by 3 publications

References 16 publications

Susceptibility to Rubella Infection and Incidence of Congenital Rubella Infection: 6 Years Retrospective Study

Susceptibility to Rubella Infection and Incidence of Congenital Rubella Infection: 6 Years Retrospective Study

Factors Predicting Rubella Vaccination and Antibody in Pregnant Women in Japan: A Report from Pregnant Women Health Initiative

Study the changes in vitamin D3, magnesium, phosphorus, parathyroid hormone and calcium levels among women positive for SARS-2 n COVID-19 concerning rubella infection

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